HETEROGENEITY AMONG HUMAN CD4+ T CELL CLONES

人类 CD4 T 细胞克隆的异质性

• 批准号: 6305136
• 负责人: DALE T UMETSU
• 金额: $ 0.06万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-12-01 至 2000-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6305136
• 关键词: allergens; alveolar macrophages; antigen presenting cell; cellular immunity; clinical research; clone cells; cytokine; helper T lymphocyte; human subject; hypersensitivity desensitization; immune tolerance /unresponsiveness; inflammation; interleukin 4; respiratory hypersensitivity; tissue /cell culture

We are examining the role of white cells that normally reside in the lungs called alveolar macrophages. We believe that such cells are involved in inhibiting immune responses and protecting the lung from inflammation that might damage the tissues. In addition, we believe that the alveolar macrophages from normal individuals differs from those of subjects with asthma.

我们正在检查通常存在于肺部的称为肺泡巨噬细胞的白细胞的作用。我们认为，这些细胞参与抑制免疫反应，保护肺部免受可能损害组织的炎症。此外，我们认为正常个体的肺泡巨噬细胞与哮喘患者的肺泡巨噬细胞不同。