SEX HORMONES, SLEEP & CIRCADIAN RHYTHMICITY IN AGING

性激素、睡眠

• 批准号: 6304099
• 负责人: PATRICIA J MURPHY
• 金额: $ 7.95万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-12-01 至 2000-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6304099
• 关键词: age difference; aging; circadian rhythms; clinical research; follicle stimulating hormone; human subject; human tissue; hypothalamic pituitary axis; luteinizing hormone; pituitary gonadal axis; sex hormones; sleep

Whether the circadian patterns of sex hormone (estrogen, testosterone, LH, FSH) release are altered in normal aging will be assessed by obtaining frequent blood samples during a 36-hour constant routine in groups of young and older individuals. The study is part of a program of research investigating whether age-related changes in the hypothalamic-pituitary-gonadal axis are associated with the types of sleep problems that are common in aging men and women.

性激素（雌激素、睾酮、黄体生成素、卵泡刺激素）释放的昼夜节律模式是否在正常衰老过程中发生改变，将通过在年轻人和老年人群体中连续36小时频繁采集血液样本来评估。这项研究是一个研究项目的一部分，该项目旨在调查下丘脑-垂体-性腺轴与年龄相关的变化是否与老年男性和女性常见的睡眠问题类型有关。