3rd Intl Symp on Serpin Biology, Structure and Function

描述(由申请者提供)：3号申请部分支持 蛇类的生物学、结构和功能国际研讨会 将于2002年6月2日至5日在伊利诺伊州芝加哥举行。这次会议将是第三次 来自世界各地的基础和临床科学家三年一度的聚会 把重点放在被称为蛇的蛋白质超家族上。 这是一个快速增长的领域，得到了研究拨款的大力支持。 来自NIH，特别是NHLBI和NCI。以前的会议是在 1996年在北卡罗来纳大学教堂山分校和加州大学 1999年，英国剑桥。本次会议将由 伊利诺伊大学芝加哥分校。重点将放在两国关系上 正常形式和变异形式的蛇类的基本性质和 这些与正常的人类生理过程和疾病之间的关系。十 会议将讨论基本的结构性和机械性问题 在正常和疾病状态下，蛇的功能或蛇的参与。34 特邀演讲者将来自四大洲，代表 菲尔德。将增加24个简短演讲(10分钟加5分钟讨论) 从提交的摘要中精选，为以下项目提供更多机会 初级科学家展示他们的工作。还将举行两次海报会议。 预计将有约200名科学家参加会议。这些遗嘱 包括博士和医学研究人员，既有基础研究人员，也有应用研究人员， 以疾病为导向的观点、兴趣和专业知识。以这种方式组织， 会议预计将实现以下目标：(一)提供 聚集研究蛇链功能的基础科学家的地点 不同的组织级别，以更好地关联蛇形结构的角色 和生理行为的机制。(二)汇聚基础 科学家和临床科学家确定蛇类在正常情况下的作用 以及病理性的人类状况，以促进治疗学的发展， 诊断性测试和治疗依赖于对基本衬线的了解 功能。(Iii)向参加者提供有关蛇纹的最新资料 生理正常和异常的作用机制和参与机制 流程，包括从提交的摘要中挑选的许多简短演讲，在 除了早先选定的主要会谈之外。(四)为所有参与者提供 有很多机会与演讲者和海报进行深入讨论 演讲者，目标是在不同学科和 鼓励合作。(五)提供有为的机会 初级科学家和少数民族在会议上发挥主要作用。

DESCRIPTION (provided by applicant): Partial support is requested for the 3rd International Symposium on the biology, structure, and function of serpins, to be held in Chicago, Illinois June 2-5, 2002. This conference will be the third triennial gathering of basic and clinical scientists from around the world to focus specifically and solely on the superfamily of proteins known as serpins. This is a rapidly-growing area that is heavily supported by research grants from NIH, particularly NHLBI and NCI. Previous meetings were held at the University of North Carolina, Chapel Hill in 1996, and at the University of Cambridge, England in 1999. The present meeting will be sponsored by the University of Illinois at Chicago. The emphasis will be on the relationship between the basic properties of serpins in both normal and variant forms and how these relate to both normal human physiological processes and disease. Ten sessions will address either basic structural and mechanistic questions of serpin function or the involvement of serpins in normal and disease states. 34 invited speakers will be from four continents and represent experts in the field. 24 additional short talks (10 minutes plus 5 minutes discussion) will be selected from submitted abstracts to provide additional opportunities for junior scientists to present their work. Two poster sessions will also be held. It is expected that about 200 scientists will attend the meeting. These will include both Ph.D. and M.D. researchers, with both basic and applied, disease-oriented perspectives, interests and expertise. Organized in this way, the conference is expected to accomplish the following goal (i) To provide a venue for bringing together basic scientists addressing serpin function at different organizational levels to better relate the roles of serpin structure and mechanism to physiological behavior. (ii) To bring together basic scientists and clinical scientists to identify the roles of serpins in normal and pathological human conditions to foster development of therapeutics, diagnostic tests and treatments that depend on understanding of basic serpin function. (iii) To provide participants with the latest information on serpin mechanisms of action and involvement in normal and abnormal physiological processes by including many short talks selected from submitted abstracts, in addition to the earlier-selected main talks. (iv) To provide all participants with many opportunities for in-depth discussion with speakers and poster presenters, with the goal of cross-fertilization between disciplines and encouragement of collaborations. (v) To provide an opportunity for promising junior scientists and minorities to play a major role in the meeting.