POSTPRANDIAL GLUCONEOGENESIS TO GLUCOSE PRODUCTION IN NORMAL VS NIDDM

正常人与 NIDDM 中餐后糖异生对葡萄糖产生的影响

• 批准号: 6421256
• 负责人: ASHOK BALASUBRAMANYAM
• 金额: $ 15.58万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-12-01 至 2001-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6421256
• 关键词: Mexican Americans; clinical research; diabetes mellitus therapy; fasting; food; gluconeogenesis; glucose metabolism; human subject; human therapy evaluation; hyperglycemia; hypoglycemic agents; liver metabolism; male; noninsulin dependent diabetes mellitus; nutrient intake activity; nutrition related tag; stable isotope

1.1. Primary Objective: Determine the safety of an enteral diet containing very low levels of methionine for treatment of patients with advanced cancer. 1.2. Secondary Objectives 1.2.1. Determine the effects of dietary methionine restriction on postprandial serum levels of methionine and other amino acids. 1.2.2. Describe any preliminary evidence of antitumor activity.

1.1.主要目的：确定含有极低水平蛋氨酸的肠内饮食治疗晚期癌症患者的安全性。1.2.次要目标1.2.1。确定饮食蛋氨酸限制对餐后血清蛋氨酸和其他氨基酸水平的影响。1.2.2.描述任何抗肿瘤活性的初步证据。