OSMOREGULATION IN POSTPARTUM WOMEN & NEWBORN INFANTS

产后女性的渗透压调节

• 批准号: 6306620
• 负责人: Michael Glenn Ross
• 金额: $ 0.1万
• 依托单位: LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-12-01 至 2000-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6306620
• 关键词: clinical research; female; human subject; newborn human (0-6 weeks); osmotic pressure; plasma; postpartum; women's health

During normal human pregnancy maternal plasma osmolality decreases significantly a response which may be of value in protecting the mother and infant from maternal dehydration. Fetal plasma osmolarity also decreases in relation to newborn values. It is unknown whether the pregnancy factors which result in a decrease in maternal plasma osmolarity primarily reduce fetal osmolarity or whether the fetal plasma osmolarity decrease is purely secondary to equilibration in response to maternal hypotonicity. The purpose of this research is to define the normal pattern of water balance and osmoregulation in the postpartum mother and newborn infant by following measures of plasma composition.

在正常的人类怀孕期间，母体血浆渗透压显著降低，这一反应可能对保护母亲和婴儿免受母体脱水有价值。胎儿血浆渗透压也相对于新生儿值降低。目前尚不清楚导致母体血浆渗透压降低的妊娠因素是否首先降低了胎儿渗透压，或者胎儿血浆渗透压降低是否纯粹继发于母体低渗反应的平衡。本研究的目的是通过以下血浆成分测量来确定产后母亲和新生儿的正常水平衡和渗透调节模式。