TOXICANTS IN HUMAN PLACENTAE AND REPRODUCTIVE OUTCOMES IN UKRAINE

我们收集了前苏联共和国乌克兰两个城市地区3 000多名孕妇的数据，据说那里的污染很严重;我们在其中2 200人分娩和住院期间采集了胎盘和母乳。 我们一直在分析这些数据，现在已经公布了所有研究污染物的结果。 一般来说，尽管有高污染的报告，但该样本中的有毒物质水平很低，无法解决对生殖结果的影响。然而，我们已经描述了这一人群的妊娠结局， 60%的怀孕被终止。 在我们的样本中，早产率非常低，但这归因于低胎龄的高胎儿死亡率和早产的高患病率（早产率仅根据活产婴儿计算）。 在这两个城市地区，早产的危险因素已经得到解决，并将继续审查低出生体重率。

We have collected data on over 3,000 pregnant women in two urban areas of Ukraine, a former Soviet republic, where pollution is reputedly high; we took placentas and breast milk from 2,200 of them during delivery and hospitalization. We have been analyzing these data and have now published findings on all the pollutants that were studied. In general, the toxicants appear at such low levels in this sample, in spite of reports of high pollution, that the effect on reproductive outcomes cannot be addressed.. However, we have described the outcome of pregnancy in this population, Sixty percent of all pregnancies were terminated. The rate of preterm birth in our sample is remarkably low, but this is ascribed to the high fetal death rate at low gestational ages, and the high prevalence of prematurity (the preterm rate is computed on live births only). Risk factors for preterm birth have been addressed in the two urban areas, and will continue with an examination of the rate of low birth weight.