NIDA STRENGTHENING WASHINGTON, DC FAMILIES GRANT

描述：(申请人摘要) 这项为期五年的研究的目标是提供关于以下方面的新知识：1) 市中心非裔美国人和白人吸毒和滥用药物的原因 青少年，以及2)最具成本效益和成本效益的 以家庭为重点的预防干预措施。本论文的研究目的是 涉及800多个高危华盛顿特区地区的随机临床试验 参加16周强化活动的7至11岁儿童家庭 家庭计划(SFP)是：1)测试 SFP的三个主要组成部分--家长培训(PT)、儿童技能 与最少接触相比，培训(CT)和家庭技能培训(FT) 对前体和物质使用/滥用的控制(MT)采用2 x 4 试验设计；2)成本效益和成本效果的估算 包括400个非裔美国家庭和400个白人家庭的SFP组成部分 以及3)经验性地测试几个相互竞争的病因和 干预设计背后的药物使用/滥用干预理论 通过分析1600名12至19岁青少年的调查研究数据， 使用结构方程模型的800个干预家庭，调解 分析、分层线性建模、潜在增长建模和 交易建模(交叉滞后的扫描电子显微镜、人工智能和 神经网络模拟)用于性别、种族和其他子组。这个 组件设计的基本原理是存在一个主要问题 关于对高危人群进行仅针对儿童的干预措施的有效性 孩子们在一起，以及与家庭一起工作的额外好处 与只接受父母培训相比，一起学习。证明了 让父母参与并与家人一起工作将是非常有价值的 为预防提供者提供的信息。其他协变量结果 将进行分析，以回答以下实际问题： 四种干预措施对不同亚群服务对象的效果。一个 强有力的流程评估，包括管理信息系统(管理信息系统) 由马里兰大学研究人员进行的WILI文档实施 处理并提供反馈，以提高实施的准确性。其他内容 卫生服务次级目标问题将通过分析 招聘、自然减员、消费者满意度、参与变量和 客户和培训师的特征与结果相关。全国七个国家 公认的顾问已同意支持特定于文化的 程序开发、实施和数据分析。

DESCRIPTION: (Applicant's Abstract) The goal of this five year research is to provide new knowledge on: 1) the causes of drug use and abuse in inner city African-American and White adolescents, and 2) the most cost-effective and cost-beneficial family-focused prevention interventions. The research aims of this randomized clinical trial involving over 800 at-risk Washington, D.C.-area families of 7 to 11 year olds in components of the 16 week Strengthening Families Program (SFP) are: 1) to test the differential efficacy of the three major components of SFP-parent training (PT), children's skills training (CT), and family skills training (FT) compared to a minimal contact control (MT) on precursors and substance use/abuse employing a 2 x 4 experimental design; 2) to estimate the cost-benefit and cost-effectiveness of the SFP components with 400 African American families and 400 White families; and 3) to empirically test several competing etiological and intervention theories of drug use/abuse underlying the intervention design by analyzing the survey research data from 1,600 12 to 19 year olds and the 800 intervention families using structural equation modeling, mediational analysis, hierarchical linear modeling, latent growth modeling, and transactional modeling (cross-lagged SEM, artificial intelligence, and neural network simulations) for gender, race, and other sub-groups. The rationale for the component design is that a major question exists concerning the efficacy of child-only interventions that group high-risk children together as well as the added benefit of working with the family together compared to parent-training only. Demonstrating the importance of involving parents and working with families would be very valuable information for prevention providers. Additional co-variate outcome analyses will be conducted to answer practical questions conceming the efficacy of the four interventions for different subgroups of clients. A strong process evaluation including a management information system (MIS) conducted by University of Maryland researchers wili document implementation process and provide feedback to improve implementation fidelity. Additional health services sub-aim questions will be addressed through analyses of recruitment, attrition, consumer satisfaction, participation variables, and client and trainer characteristics linked to outcomes. Seven nationally recognized consultants have agreed to support the culturally-specific program development, implementation, and data analyses.