FEASIBILITY OF BIOLOGICAL MEASUREMENT IN DRUG SURVEYS

描述(改编自申请人的摘要)：这项工作将有助于 在社会层面更有效地预防和治疗药物滥用 通过提高药物滥用测量的准确性。具体地说，这项研究 将就合并的可行性提供明确的答案 在普通人群中对药物使用情况的生物测量 关于药物滥用的家庭调查。建议的研究将评估 三种不同生物测量方法的可行性和实用性 作为辅助检查的程序(头发、唾液和尿液检测) 关于药物滥用的家庭调查。这项研究将比较相对的 不同生物检测方法在调查中的可接受性 通过对600名随机选择的受试者进行家庭调查 居住在芝加哥市。通过将受试者随机分配给 高激励或低激励的药物测试条件，本研究将评估其作用 关于参与生物测量的替代激励战略。 通过定量和定性分析，本研究将评估 无数相关的主题、采访条件和程序变量 参与家庭调查的药物测试。这项研究将检查 事先接触药物测试的影响和对药物测试的看法 参与生物测量意愿的准确性。这项研究 也会了解成年人是否愿意同意 在儿童中进行类似的药物测试。可选的统计程序 从多个生物学指标构建流行率估计器将是 探索过了。来自生物评估的结果将与 在有声计算机辅助下回答有关药物使用的问题 在生物评估之前的自我访谈。考虑到 影响药检参与度的因素，这些比较将被用于 评估普通人群中未报告吸毒情况的程度。 与药物使用漏报相关的主体和药物使用变量将是 完全分析过了。毛发测试的效用将通过以下方式进一步评估 检查新的确认过程(负离子筛选)是否产生 提高了检测大麻代谢物的灵敏度。

DESCRIPTION (Adapted from the Applicant's Abstract): This work will facilitate more effective drug abuse prevention and treatment efforts on a societal level by enhancing the accuracy of drug abuse measurement. Specifically, this study will provide definitive answers regarding the viability of incorporating biological measurement of drug use in the context of general population household surveys on drug abuse. The proposed study will evaluate the feasibility and utility of three different types of biological measurement procedures (hair, saliva, and urine testing) to be used as an adjunct to a household survey on drug abuse. This study will compare the relative acceptability of the different biological test methods among survey participants through household surveys of 600 randomly selected subjects residing in the City of Chicago. By randomly assigning subjects to either a high or low incentive drug test condition, this study will evaluate the role of alternative incentive strategies on participation in biological measurement. Through quantitative and qualitative analyses, this study will assess the myriad of subject, interview condition, and procedural variables associated with drug test participation in household surveys. This study will examine impact of prior exposure to drug testing and perceptions about drug testing accuracy on willingness to participate in biological measurement. The study will also gain an understanding of adult willingness to provide consent for similar drug testing in children. Alternative statistical procedures for constructing prevalence estimators from multiple biological measures will be explored. Results derived from biological assessments will be compared with responses to questions about drug use provided in an Audio Computer Assisted Self Interview that precedes the biological assessment. Taking into account factors influencing drug test participation, these comparisons will be used to evaluate the extent of underreporting of drug use in the general population. Subject and drug use variables associated with drug use underreporting will be fully analyzed. The utility of hair testing will be further evaluated by examining whether a new confirmation process (negative ion screening) yields increased sensitivity for detecting marijuana metabolites.