Combining advanced polymer-peptide conjugate synthesis with advanced mass spectrometry characterization - a collaborative study.

本项目涉及使用先进的质谱方法合成和表征聚合物肽自组装缀合物。使用的方法包括超高分辨率质谱，先进的串联质谱（ExD， IRMPD， CAD）和二维质谱。除了可以更好地控制这些材料合成的化学过程外，先进的分析方法还可以提供比以前在聚合物材料上获得的更全面的数据。该项目由位于Macclesfield的Astra Zeneca的Peter O'Connor教授、Sebastien Perrier教授和Anthony Bristow博士合作完成。

This project involves study of synthesis and characterisation of polymer-peptide self-assembling conjugates using advanced mass spectrometry methods. The methods to be used include ultra high resolution mass spectrometry, advanced tandem mass spectrometry (ExD, IRMPD, CAD), and two dimensional mass spectrometry. In addition to allowing better control of the chemistry of synthesis of these materials, the advanced analytical methods should allow far more comprehensive data than ever previously achieved on polymeric materials.This project is a collaborative project among Prof. Peter O'Connor, Prof. Sebastien Perrier, and Dr. Anthony Bristow at Astra Zeneca in Macclesfield.