MBRS PROGRAM

MBRS计划

• 批准号: 6342712
• 负责人: Sandra Bonetti
• 金额: $ 37.27万
• 依托单位: COLORADO STATE UNIVERSITY-PUEBLO
• 依托单位国家: 美国
• 财政年份: 1981
• 资助国家: 美国
• 起止时间: 1981-08-25 至 2002-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6342712
• 关键词: minority institution research support

This proposal requests continued support for the highly successful MBRS Program at the University of Southern Colorado (USC). The goals of this program are to increase the number of minority students attaining advanced degrees in the biomedical sciences and to enhance research opportunities for faculty and students at USC, an institution that serves a large minority community and student population. The development of students into productive, mature, and ethical scientists is a primary objective. To achieve these goals, this proposal describes eight research projects spanning the areas of biology, chemistry, psychology, and human performance studies. The eight research projects include two in chemistry, two in biology, and one each in biochemistry and human performance studies. One of the biology projects investigates the role of the M1 metallo- aminopeptidase gene in yeast cell physiology. The second biology project examines the effect of uterine proteinase activity on embryo implantation. The biochemistry project seeks to characterize and determine the function of fungal acid phosphatases that exhibit a high degree of sequence homology to the mammalian tartrate-resistant acid phosphatases that are overly expressed in cell leukemia. One chemistry project explores synthetic routes to medicinal compounds via fluorination reactions. The second chemistry project's objective is to advance biomedical research through the design of selective and specific materials for chromatographic separations of pharmaceuticals. One of the psychology projects investigates the function of neuropeptides and their receptors in the control of voluntary alcohol preferences in an animal model of ethanol consumption. The second psychology project examines the relationship between salt appetite and neural physiological changes in the rat. The human performance studies project examines the psychological and social factors that contribute to maintenance of physical activities and health in a Hispanic church-based population. The diversity of the projects and the faculty researchers is expected to attract and actively engage students in productive research experiences as preparation for graduate biomedical programs.

该建议要求继续支持非常成功的 科罗拉多大学（USC）的MBRS计划。 目标 这个计划的是增加少数族裔学生的数量 在生物医学科学中获得高级学位并增强 南加州大学的教师和学生的研究机会， 为大型少数民族社区和学生服务的机构 人口。 将学生发展成富有成效，成熟和 道德科学家是一个主要目标。 为了实现这些目标， 该提案描述了八个跨越领域的研究项目 生物学，化学，心理学和人类绩效研究。 八项研究项目包括化学方面的两个，两个生物学，两个研究项目， 每个都在生物化学和人类绩效研究中。 之一 生物学项目调查了M1金属的作用 酵母细胞生理学中的氨基肽酶基因。 第二个生物学 项目检查子宫蛋白酶活性对胚胎的影响 植入。 生物化学项目旨在表征和 确定表现出A的真菌酸磷酸酶的功能 抗哺乳动物防sttrate的高度序列同源 在细胞白血病中过于表达的酸性磷酸酶。 一 化学项目探讨了与药用化合物的合成路线 通过氟化反应。 第二个化学项目的目标 是通过设计性设计和 色谱分离的特定材料 药品。 心理学项目之一调查了 神经肽及其受体在控制中的功能 乙醇动物模型中的自愿性酒精偏好 消耗。 第二个心理学项目检查了关系 盐食欲与大鼠的神经生理变化之间。 人类绩效研究项目研究了心理和 有助于维持体育活动的社会因素 与西班牙裔教会人口中的健康。 多样性 预计项目和教师研究人员将吸引和 积极吸引学生参与生产研究经验 为研究生生物医学计划做准备。