MBRS Program-University of Southern Colorado

MBRS项目-南科罗拉多大学

• 批准号: 6521893
• 负责人: Sandra Bonetti
• 金额: $ 33.2万
• 依托单位: COLORADO STATE UNIVERSITY-PUEBLO
• 依托单位国家: 美国
• 财政年份: 1981
• 资助国家: 美国
• 起止时间: 1981-08-25 至 2006-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6521893
• 关键词: minority institution research support

DESCRIPTION (provided by applicant): This proposal requests support for a new SCORE Program to replace the existing, traditional MBRS grant at the University of Southern Colorado (USC). The three departments participating in this new SCORE application are the Departments of Biology, Chemistry, and Psychology; each of these departments has submitted two research subprojects. The overall goals of this program are to enhance institutional biomedical research capabilities and to attract and recruit underrepresented minority participation in the biomedical research enterprise. The individual and program goals support this mission. The specific goals of the overall program are as follows: (1) to increase the research competitiveness or productivity of SCORE research faculty in the Departments of Biology, Chemistry, and Psychology; and (2) to increase the participation of faculty and students on campus, especially minorities, in biomedical research. Measurable objectives and activities accompany each of these goals. For the first specific goal, productivity will be measured in terms of numbers of refereed presentations, publications, grant submissions, and collaborations. A specific standard of 3 publications and 10 presentations has been instituted as the minimum standard for the SCORE Program subprojects. For the second specific activity, the number of supplemental applications to SCORE and participation of USC faculty in grantmanship workshops, seminars, and faculty research roundtables will be used to assess the achievement of the goal. An evaluation plan and an external advisory committee are vital components of this grant and will enhance the activities proposed and will promote the completion of the goals. To achieve the overall SCORE program goals, six subprojects and an administrative component are participating in this grant. The six research projects include two in Biology, two in Chemistry, and two in Psychology. One of the biology projects examines the mechanisms of psoralen-induced reproductive toxicity. The second biology project, a reproductive physiology project, is a comparative study of events surrounding the zona escape in mammals. The Chemistry projects are in Biochemistry and Analytical Chemistry. The biochemistry project examines fungal cell surfaces by using standard chemical methods and the recently developed technique of atomic force microscopy, with the potential of providing valuable information for the design of antifungal agents. The analytical project characterizes novel silica surfaces that may be potentially used in separation of complex biological mixtures and pharmaceuticals. One of the Psychology projects examines the interactions of peptides with alcohol satiation and the second investigates the relationship between reading disabilities in children and neuroanatomy.

描述(由申请人提供)：本提案请求支持一个新的SCORE计划，以取代南科罗拉多大学(USC)现有的、传统的MBR拨款。参加这次新分数申请的三个系是生物、化学和心理学系，每个系都提交了两个研究子项目。该计划的总体目标是加强机构生物医学研究能力，并吸引和招募生物医学研究企业中代表不足的少数群体参与。个人和项目目标支持这一使命。整个计划的具体目标如下：(1)提高生物、化学和心理学系的成绩研究人员的研究竞争力或生产力；(2)增加校园内教职员工和学生的参与，特别是少数族裔，参与生物医学研究。可衡量的目标和活动伴随着这些目标中的每一个。对于第一个具体目标，生产率将根据被引用的演示文稿、出版物、赠款提交和合作的数量来衡量。制定了3份出版物和10份演示文稿的具体标准，作为评分方案分项目的最低标准。对于第二项具体活动，将使用补充申请计分的数量以及南加州大学教职员工参加助学金研讨会、研讨会和教职员工研究圆桌会议的情况来评估目标的实现情况。评价计划和外部咨询委员会是这笔赠款的重要组成部分，将加强拟议的活动，并将促进完成各项目标。为了实现总体成绩方案目标，六个子项目和一个行政部分将参与这笔赠款。这六个研究项目包括两个生物学，两个化学和两个心理学。其中一个生物学项目研究了补骨脂素引起的生殖毒性的机制。第二个生物学项目是生殖生理学项目，是对哺乳动物小带逃逸周围事件的比较研究。化学项目是生物化学和分析化学。生物化学项目使用标准的化学方法和最近发展起来的原子力显微镜技术来检查真菌细胞表面，有可能为抗真菌药物的设计提供有价值的信息。该分析项目表征了可能用于分离复杂生物混合物和药物的新型二氧化硅表面。其中一个心理学项目研究了肽与酒精饱足的相互作用，第二个项目调查了儿童阅读障碍与神经解剖学之间的关系。