A PROSPECTIVE STUDY OF ALASKA NATIVES & AMERICAN INDIANS

描述：(申请人提供)慢性病患病率各有不同 美国印第安人和阿拉斯加原住民(AIAN)和美国 白人人口的原因在很大程度上是未知的。尽管很少有 了解影响AIAN慢性病的因素，发病率 大多数慢性病都在增加。这份为期4年的提案侧重于 制定AIAN队列，以更好地了解 AIAN之间存在的发病率和风险因素知识差异 和美国白人人口。这项建议的目的是制定有效的 以及获得饮食、体力活动和生活方式的可靠方法 并确定最有效和最有效的招聘方式， 登记和跟踪来自不同人群的研究参与者。我们会工作的 与当地社区一起制定适合文化的调查问卷， 将准确捕捉饮食摄入量、体力活动模式、生活方式 和文化习惯。我们将与当地医疗服务提供者和印度人合作 健康服务机构从医疗记录中获取与研究有关的数据，并 建立以人口为基础的招聘方式。从年第3年开始 在提案中，我们将启动招聘和数据收集、测试 各种协议，以确定最有效和最有效的方式进行 这项研究。我们预计有2000名阿拉斯加原住民，3000名来自 纳瓦霍民族和来自平原州的1500名美国印第安人将 在24个月的时间段内注册。需要此数量的参与者才能 充分测试我们招收大量个人以及 确定登记给诊所带来的潜在负担。少校 AIAN队列的科学目标是确定饮食、身体状况 活动，以及其他与发展有关的生活方式和文化因素 以及慢性疾病的进展，如癌症、心血管疾病、 中风、2型糖尿病、慢性肺病和呼吸系统疾病及相关疾病 这些疾病的死亡率。研究数据将用于评估健康状况 并确定处于各种健康状况风险中的人群。 将使用纵向数据来确定对健康有贡献的因素 并预防疾病。AIAN队列将作为一种资源来加强 AIAN学生对健康感兴趣的研究和培训活动 研究、健康教育和一般公共卫生。

DESCRIPTION: (Provided by applicant) Rates of chronic diseases vary substantially between American Indians and Alaska Natives (AIANs) and U.S. white populations for reasons that are largely unknown. Although little is known about factors that affect chronic diseases in AIANs, incidence rates for most chronic diseases are increasing. This 4-year proposal focuses on the development of an AIAN cohort to obtain a better understanding of the disparity in disease rates and risk factor knowledge that exist between AIANs and U.S. white populations. The purpose of this proposal is to develop valid and reliable methods to obtain diet, physical activity, and lifestyle information and to determine the most efficient and effective ways to recruit, enroll, and track study participants from diverse populations. We will work with local communities to develop culturally appropriate questionnaires that will accurately capture dietary intake, physical activity patterns lifestyle and cultural habits. We will work with local health providers and the Indian Health Service to access relevant study-related data from medical records and we will establish population-based recruitment methods. Starting in year 3 of the proposal, we will initiate recruitment and data collection, testing various protocols to determine the most efficient and effective way to conduct the study. We project that 2000 Alaska Natives, 3000 American Indians from the Navajo Nation, and 1500 American Indians from the Plains states will be enrolled over a 24-month time period. This number of participants is needed to adequately test our ability to enroll large numbers of individuals as well as determine potential burden to clinics as a result of enrollment. The major scientific goal of the AIAN cohort is to determine how diet, physical activity, and other lifestyle and cultural factors relate to the development and progression of chronic diseases such as cancer, cardiovascular disease, stroke, Type 2 diabetes, chronic lung and respiratory diseases, and related mortality from these diseases. Study data will be used to assess health status and identify groups of the population at risk for various health conditions. Longitudinal data will be used to identify factors that contribute to health and prevent disease. The AIAN cohort will serve as a resource to enhance research and training activities of AIAN students interested in health research, health education, and general public health.