Electroretinogram recordings of human scotopic dark adaptation following intense bleaching exposures

强烈漂白暴露后人类暗适应的视网膜电图记录

• 批准号: nhmrc : 268032
• 负责人: Prof Trevor Lamb
• 金额: $ 18.15万
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2004
• 资助国家: 澳大利亚
• 起止时间: 2004-01-01 至 2006-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/electroretinogram-recordings-human-bleaching-exposures/82713
• 关键词: Electroretinogram; recordings; human; scotopic; dark

After a human subject has been exposed to intense illumination, it can take many minutes for the eye to regain full sensitivity, as one experiences (for example) when entering a dark cave after being out on a bright sunny beach. This project will investigate the processes that occur in the cells of retina lining the back of the eye, that prevent the instantaneous recovery of vision following intense illumination. Electrical recordings will be made from the eyes of normal individuals, using new techniques that allow the activity of different types of nerve cell in the retina to be monitored. The study will determine how it is that events in the light-detector cells of the eye (the rod and cone photoreceptors) influence the activity of subsequent nerve cells in the visual system, and how these events contribute to the poor vision that one experiences following bright lights.

当一个人暴露在强烈的光照下后，眼睛可能需要几分钟才能恢复完全的敏感性，就像一个人在阳光明媚的海滩上进入黑暗的洞穴时所经历的那样。这个项目将研究在眼睛后部的视网膜细胞中发生的过程，这些过程阻止了强烈照明后视力的瞬时恢复。电子记录将从正常人的眼睛，使用新技术，使不同类型的神经细胞的活动在视网膜上进行监测。这项研究将确定眼睛光探测器细胞（视杆细胞和视锥细胞）中的事件如何影响视觉系统中随后神经细胞的活动，以及这些事件如何导致人们在明亮的灯光下经历的视力不良。