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CORE--Mechanisms of toxicity and cell death

CORE--Mechanisms of toxicity and cell death
核心--毒性和细胞死亡机制
批准号：
6495700
负责人：
TERRENCE J. MONKS
金额：
$7.35万
依托单位：
UNIVERSITY OF TX MD ANDERSON CAN CTR
依托单位国家：
美国
项目类别：
财政年份：
2001
资助国家：
美国
项目状态：
已结题
起止时间：
2001-04-01 至 2002-03-31
来源：
https://reporter.nih.gov/project-details/6495700
关键词：
apoptosis biological signal transduction biomedical facility cell cycle cytotoxicity environmental health environmental toxicology oxidative stress pathologic process toxin metabolism

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英文摘要
Description: This core was initially named "Mechanisms of Chemical Disposition and Toxicity", and concentrated on reactive oxygen species and their role in cytotoxicity. However, four members have left the core while Drs. Kline, Sanders, Richburg and Miller joined the core, the latter two being new appointments at UT Austin. Finally, Dr. Walker has become a secondary member to bring the total number of members to ten. The core is headed by Dr. Terrence Monks. Eight of the ten members are located at UT-A. The stated themes of the core are: (1) identification of the cellular and molecular mechanisms by which chemicals modulate programmed cell death, and the relationship between these effects and environmental-induced diseases, and (2) chemical-induced modulation of stress signaling pathways and cell cycle progression.
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  • 项目类别：
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    $37.48万
  • 财政年份：
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  • 负责人：
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  • 依托单位：
    WAYNE STATE UNIVERSITY
Alleviating Reactive Carbonyl Species-Induced Progenitor Cell Dysfunction in Diabetic Wound Healing
  • 批准号：
    10221677
  • 项目类别：
  • 资助金额：
    $37.48万
  • 财政年份：
    2019
  • 负责人：
    TERRENCE J. MONKS
  • 依托单位：
    WAYNE STATE UNIVERSITY
Hepatic Metabolism and Susceptibility to Ecstasy Toxicity
  • 批准号：
    8078934
  • 项目类别：
  • 资助金额：
    $32.17万
  • 财政年份：
    2008
  • 负责人：
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  • 依托单位：
    UNIVERSITY OF ARIZONA
Hepatic Metabolism and Susceptibility to Ecstasy Toxicity
  • 批准号：
    7860382
  • 项目类别：
  • 资助金额：
    $33.16万
  • 财政年份：
    2008
  • 负责人：
    TERRENCE J. MONKS
  • 依托单位：
    UNIVERSITY OF ARIZONA
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