Diagnostic Electron Microscopy (EM)

诊断电子显微镜 (EM)

• 批准号: 6558556
• 负责人: MARIA TSOKOS
• 金额: --
• 依托单位: DIVISION OF CLINICAL SCIENCES - NCI
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6558556
• 关键词: Ewing's tumor; bioimaging /biomedical imaging; colorectal neoplasms; diagnosis design /evaluation; diagnosis quality /standard; diagnosis service; human tissue; neoplasm /cancer classification /staging; neoplasm /cancer diagnosis; patient oriented research; pediatric neoplasm /cancer; transmission electron microscopy

Transmission electron microscopy (EM) is used as an adjunct procedure in the diagnosis of a wide range of neoplastic and non neoplastic diseases and can be extremely useful in well chosen diagnostic dilemmas. The main objectives of the diagnostic EM service are: (1) to provide high quality EM diagnostic services to NCI- and NIH-supported clinical diagnostic and treatment protocols (2) to help elucidate the pathogenesis of disease processes studied in these protocols (3) to teach pathology residents and fellows the application of EM in the diagnosis of human diseases and (4) to provide electron microscopic expertise to the NIH scientific community. The last year's accomplishments are summarized below: (1) A total of 100 patient tissues were processed and diagnosed by EM. The service is regularly inspected and certified by CAP. (2) Research specimens with multiple samples per specimen were processed and evaluated, resulting in 7 publications. (3) Invitation by the Society of Ultrastructural Pathology to lecture in the society's companion meeting on "the routine use of electron microscopy and other adjunct diagnostic techniques in pediatric neoplasms" (US-CAP meeting, Chicago, Feb. 24, 2002)

透射电子显微镜（EM）是一种辅助手段，用于诊断各种肿瘤性和非肿瘤性疾病，在精心选择的诊断困境中非常有用。EM诊断服务的主要目标是：（1）为NCI和NIH支持的临床诊断和治疗方案提供高质量的EM诊断服务（2）帮助阐明这些方案中研究的疾病过程的发病机制（3）教导病理学住院医师和研究员EM在人类疾病诊断中的应用和（4）为NIH科学界提供电子显微镜专业知识。过去一年的成就概述如下： (1)共100例患者组织进行了EM处理和诊断。该服务由CAP定期检查和认证。 (2)对每个样本多个样本的研究样本进行了处理和评估，产生了7篇出版物。 (3)应超微病理学会邀请，在该学会的同伴会议上发表关于“电子显微镜和其他辅助诊断技术在儿科肿瘤中的常规应用”的演讲（US-CAP会议，芝加哥，2002年2月24日）