Follow-up--Estimate Incidence of Mobility Disability

随访——估计行动障碍的发生率

• 批准号: 6521799
• 负责人: Jack M Guralnik
• 金额: --
• 依托单位: NATIONAL INSTITUTE ON AGING
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6521799
• 关键词: aging; functional ability; gait; human old age (65+); human subject; longitudinal human study; patient oriented research; prognosis; rehabilitation

The overarching goals of this research are to evaluate follow-up status, 1 to 2 years after baseline, of a cohort of persons aged 75-85 at baseline who were found to have functional limitations (EPESE performance battery score of 4-9) but who were able to walk 400 meters in a test done in the Hebrew Home rehabilitation unit. Specific questions to be addressed include: 1.What is the incidence of inability to walk 400 meters in at-risk older persons who were found to be able to walk this far at baseline? 2.What are the main chronic diseases, impairments, and demographic characteristics which predict incident mobility loss? 3.What questions can be asked to impute who will be unable to walk 400 meters in an objective test of walking this distance in the clinic. This methodologic work may allow for the imputation of mobility disability status in persons in a future clinical trial who refuse to come into the clinic or are not physically capable of coming to the clinic.

这项研究的首要目标是评估基线后1至2年的随访状况，即基线年龄在75-85岁之间的一组人，他们被发现有功能限制(EPESE性能电池评分4-9)，但在希伯来人之家康复单元进行的测试中能够行走400米。需要解决的具体问题包括： 1.在基线条件下能够走这么远的高危老年人中，无法行走400米的发生率是多少？2.主要的慢性病、损伤和人口学特征是什么，可以预测事件中的行动能力丧失？3.在诊所进行步行400米的客观测试时，可以问什么问题来确定谁将无法行走400米？这一方法论工作可能允许在未来的临床试验中对拒绝来诊所或身体上没有能力来诊所的人的行动障碍状况进行推定。