COMBINED VISUAL DISPLAY & EYE TRACKING SYSTEM FOR HIGH FIELD FMRI STUDIES

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• 批准号: 6480907
• 负责人: Paul Douglas Gamlin
• 金额: $ 15.58万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-01 至 2003-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6480907
• 关键词: bioengineering /biomedical engineering; biomedical resource; cognition; communication behavior; magnetic resonance imaging; nervous system

An open question in our understanding of language processing and speech production is whether a common phonological lexicon within the brain serves both speech production and word recognition. Data from studies of patients with lesions provide conflicting evidence about the neural substrates mediating phonological access, supporting both the common lexicon and dual lexicons hypotheses. fMRI studies using Echo-planar imaging (EPI) will be performed in 10 right-handed subjects. Our fMRI study uses tasks that systematically evaluate both input and output phonological processing, and should help resolve the uncertainty about the number of phonological lexicons and their structure and function. Four tasks will be applied in these studies: Auditory discrimination, Rhyme judgments, Lexical decisions, and Synonym judgments. The project is funded by an NIH R03 (1/01/98 to 12/31/98). Preliminary studies have been performed to verify the operation of the auditory stimulus hardware. The initial studies performed in this project will likely lead to more comprehensive studies in the future. This research may result in a better understanding of the brain pathways involved in phonological access for speech production and for word recognition, and may contribute to a better understanding of language development and disorders.

在我们对语言处理和语言处理的理解中一个悬而未决的问题 语音产生是指是否有一个共同的语音词汇在 大脑既服务于语音产生，也服务于单词识别。数据来自 对皮损患者的研究提供了相互矛盾的证据 神经底物调节语音通路，支持两者 常见词汇和双词汇假说。 使用回声平面成像(EPI)的功能磁共振研究将在 10名右撇子受试者。我们的fMRI研究使用的任务是 系统地评估输入和输出语音处理， 并应有助于解决有关数量的不确定性 音系词汇及其结构和功能。四项任务 将在这些研究中应用：听觉辨别，韵律 判断、词汇判断和同义词判断。 该项目由NIH R03(1998年1月1日至1998年12月31日)资助。 已进行初步研究，以核实该系统的运作 听觉刺激硬件。 在这个项目中进行的初步研究可能会导致 在未来进行更全面的研究。这项研究可能会导致 更好地理解与语音有关的大脑通路 用于语音产生和单词识别的访问，并且可以 有助于更好地了解语言发展和 精神错乱。