Non-contact ACL injury in sport--mechanisms & prevention

运动中非接触性ACL损伤--机制

• 批准号: 6512220
• 负责人: ANTONIE J. VAN DEN BOGERT
• 金额: $ 24.61万
• 依托单位: CLEVELAND CLINIC FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-06-01 至 2004-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6512220
• 关键词: alternatives to animals in research; biomechanics; computer simulation; consumer product; disease /disorder etiology; female; foot; gender difference; human subject; injury prevention; joint ligament; knee; limb movement; male; mathematical model; model design /development; neuromuscular function; patient oriented research; sports injury; surface property; university student; women's health; young adult human (21-34)

DESCRIPTION: (Verbatim from application) Rupture of the anterior cruciate injury typically occurs during a rapid deceleration or change of direction, without contact with other players. Landing, stopping, and sidestepping are typical examples of such movements. Surgical repair is costly and requires extensive rehabilitation. The long-term prognosis is a high risk of osteoarthritis, which may eventually lead to total knee replacement. Women have a two to seven times larger risk for ACL injury in sport than men. Many factors play a role in the injury mechanism: anatomy, tissue strength, hormonal effects, equipment (footwear) design, and movement coordination. The latter two factors are amenable to intervention and offer potential prevention strategies. However, specific quantitative knowledge of their effects on ACL injury is not available and a controlled experimental study of the injury mechanisms is required. Such studies cannot be performed in human subjects, for ethical reasons. Animal models are unsuitable because these do not simulate the mechanics of the movement. On the other hand, the mechanical properties of the musculoskeletal system are sufficiently well known to make computer simulations feasible. Hence, the objectives of this project are (1) to develop valid computational models for ACL injury during stopping, landing, and cutting movements, (2) to use these models to determine the effects of variations in movement control on the rate of ACL injury during these movements, and (3) to predict the protective effect of specific modifications of shoe friction on rate of ACL injury and the associated effect on performance. We expect to find that inaccuracies in movement coordination, as observed in human subjects, can lead to ACL rupture and that that this explains the larger risk for females. Further more, we expect to find that these injuries can be effectively prevented by coordination training or reduction of shoe-ground friction coefficients for females. A secondary hypothesis is that the desired modifications can be achieved without impairing performance. Results of this research can be translated into recommendations and specific goals for coordination training, making it possible to use biofeedback, and development of gender-specific footwear safety standards for female athletes. The long-term impact on public health is a reduction in knee ligament injuries in sport, especially in females, and the ensuing long-term disabilities due to osteoarthritis in a relatively young population.

描述：(逐字申请)前十字韧带断裂 损伤通常发生在快速减速或改变方向时， 而不与其他玩家接触。着陆、停下来和躲避是 这类运动的典型例子。外科修复费用昂贵，而且需要 广泛康复。长期预后是一种高风险的 骨关节炎，最终可能导致全膝关节置换术。女人有 运动中前交叉韧带损伤的风险是男性的两到七倍。很多因素 在损伤机制中发挥作用：解剖学、组织力量、激素 效果、设备(鞋类)设计和运动协调。后两者 这些因素易于干预，并提供了潜在的预防策略。 然而，关于它们对前交叉韧带损伤的影响的具体定量知识并不是 对损伤机制的现有和对照实验研究是 必填项。这样的研究不能在人类受试者身上进行，因为伦理 理由。动物模型是不合适的，因为它们不能模拟 运动的机械学。另一方面，材料的力学性能 肌肉骨骼系统足够广为人知，可以进行计算机模拟 可行。因此，本项目的目标是(1)开发有效的 前交叉韧带在停车、着陆和切割过程中损伤的计算模型 运动，(2)使用这些模型来确定变化的影响 运动控制在这些运动中的前交叉韧带损伤率； 预测特定修改鞋面摩擦力的保护效果 前交叉韧带损伤率及其对运动成绩的影响。 我们预计会发现运动协调方面的不准确，如在 人类受试者，会导致前交叉韧带断裂，这就解释了 对女性来说是有风险的。此外，我们希望发现这些伤害可能是 通过协调训练或减少鞋底有效地防止 女性的摩擦系数。一个次要假设是，所需的 可以在不影响性能的情况下实现修改。 这项研究的结果可以转化为建议和具体 协调培训的目标，使使用生物反馈成为可能，以及 为女运动员制定针对性别的鞋类安全标准。 对公众健康的长期影响是减少膝盖韧带的损伤 在体育运动中，特别是在女性中，以及随之而来的因以下原因造成的长期残疾 相对年轻人群中的骨性关节炎。