Elucidating unique molecular mechanisms involved in HIV-1 subtype C pathogenicity
Elucidating unique molecular mechanisms involved in HIV-1 subtype C pathogenicity
批准号:
nhmrc : 1022066
负责人:
A/Pr Paul Ramsland
金额:
$47.41万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2014-12-31
中文摘要
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英文摘要
Most people infected with human immunodeficiency virus (HIV) have subtype C virus (C-HIV) and live in Southern Africa and Central Asia. These regions are where the HIV pandemic is at its worst. However, we know very little about C-HIV. We have evidence that C-HIV evolves differently compared to other HIV-1 subtypes, which impacts the way it leads to AIDS. This project aims to characterise these unique molecular mechanisms, which may lead to vaccines and drugs that are optimised for C-HIV.
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会议论文
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structural investigations of carbohydrate recognition by antibodies with emerging importance in medecine
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Does Galalpha(1,3)Gal still play a role in xenograft destruction after the production of Gal knockout pigs?
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负责人:孙鹏
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依托单位: