Electromagnetic spectrum on biomarkers of skin function and intervention of such effects

皮肤功能生物标志物的电磁波谱及其干预措施

• 批准号: 1959726
• 金额: --
• 依托单位: Newcastle University
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2017
• 资助国家: 英国
• 起止时间: 2017 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-1959726
• 关键词: Electromagnetic; spectrum; biomarkers; skin; function

Sunscreens and related compounds are known to slow down the process of skin ageing caused by exposure to ultraviolet radiation (UVR) in sunlight. The sunscreens and related compounds also contain actives which contribute the skin protection and anti-ageing of the products. The objectives are to determine the biochemical effects of aspects of the electromagnetic spectrum on biomarkers of skin function and its commercial application towards the modulation and intervention of such effectsThis science together with the direct links with Croda and its benefit to the UK market and beyond fits very well with the BBSRC vision to lead world-class 21st century bioscience, promoting innovation in the bioeconomy and realising benefits for society within and beyond the UK. The project clearly complies with the BBSRC vision statement of "Staying healthier for longer as lifespans increase and society ages"; the BBSRC strategic research priority of "bioscience for health" and the BBSRC enabling theme of "partnerships".

众所周知，防晒霜和相关化合物可以减缓因暴露于阳光中的紫外线辐射（UVR）而导致的皮肤老化过程。防晒剂和相关化合物还含有有助于产品保护皮肤和抗衰老的活性物质。目标是确定电磁频谱对皮肤功能生物标志物的生物化学效应及其在调节和干预此类效应方面的商业应用。这一科学与禾大的直接联系及其对英国市场的益处以及其他方面非常符合BBSRC引领世界级21世纪世纪生物科学的愿景，促进生物经济的创新，并为英国内外的社会实现利益。该项目显然符合生物安全与健康研究中心的愿景声明“随着寿命的延长和社会老龄化，保持更长时间的健康”;生物安全与健康研究中心的战略研究优先事项“生物科学促进健康”和生物安全与健康研究中心的“伙伴关系”赋能主题。

项目成果

Visible, infrared and ultraviolet components of sunlight; effects on damage biomarkers in human skin cells

太阳光的可见光、红外线和紫外线成分；

• 发表时间: 2020
• 作者: Bonn C A

Individual and combined effects of the infrared, visible, and ultraviolet light components of solar radiation on damage biomarkers in human skin cells

• DOI: 10.1096/fj.201902351rr
• 发表时间: 2020-01-16
• 期刊: FASEB JOURNAL
• 影响因子: 4.8
• 作者: Hudson, Laura;Rashdan, Eyman;Birch-Machin, Mark A.
• 通讯作者: Birch-Machin, Mark A.