Endometriosis: defining mechanisms for novel risk loci on chromosomes 7p15.2 and 1p36

子宫内膜异位症：染色体 7p15.2 和 1p36 上新风险位点的定义机制

• 批准号: nhmrc : 1026033
• 负责人: A/Pr Dale Nyholt
• 金额: $ 40.88万
• 依托单位: Queensland Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/endometriosis-defining-mechanisms-7p152-1p36/110462
• 关键词: Endometriosis; defining; mechanisms; novel; risk

We recently identified two novel genomic regions with robust evidence for associaiton with endometriosis. The result does not give immediate insights into the genes or pathways contributing to disese because the genes in each region assocaited with increased risk need to be clearly identified. This project aims to find the gene or genes responsible in each region to help develop reliable disease biomarkers and effective preventative and therapeutic strategies for this important disease.

我们最近发现了两个新的基因组区域与子宫内膜异位症相关的强有力的证据。这一结果并不能立即揭示导致疾病的基因或途径，因为每个区域中与风险增加相关的基因需要明确识别。该项目旨在找到每个区域的基因或基因，以帮助开发可靠的疾病生物标志物和有效的预防和治疗策略。