The use of super-resolution microscopy to analyse delivery of extracellular vesicle carge

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Extracellular vesicles (EVs) are emerging as important regulators of a variety of normalbiological processes in cells and organisms across the eukaryotic and prokaryotickingdoms. They are small vesicles that can carry several types of cargo, including RNA,proteins and lipids; they can be released by one cell and taken up by nearby or moredistantly located cells. This transfer is associated with the delivery of EV cargo into therecipient cell and an ensuing biological response; EVs therefore represent a hithertounder-explored mechanism of intercellular communication.