The mitigation of primary blast injury: development of energy and weight efficient systems

减轻初级爆炸伤害:开发节能和重量有效的系统

基本信息

  • 批准号:
    2012772
  • 负责人:
  • 金额:
    --
  • 依托单位:
  • 依托单位国家:
    英国
  • 项目类别:
    Studentship
  • 财政年份:
    2017
  • 资助国家:
    英国
  • 起止时间:
    2017 至 无数据
  • 项目状态:
    已结题

项目摘要

The literature related to injuries from blast weapons, in both military and terrorist scenarios, indicate the extensive incidence of a range of injuries, from Blast Lung to Bowel and other soft tissue damage. In particular, clinical reports from Israel, indicate the uniqueness and significant mortality from lung and bowel injury from blast. These are often associated with a range of added complications due to infection from widespread tearing of tissues.The increased incidence of Primary blast injury was the major driver for the formation of CBIS. Progress has been made on the understanding of the limits of the human body with respect to the forces and duration of blast in areas of Blast Lung.A logical extension is to reduce the incidence of such forms of blast injury in the first instance. This project is to directly address the area of blast mitigation. Reduction of the initial blast insult is obviously and widely reported as a clear method of increasing survivability. However, while many body armour systems function well against ballistic threats, research indicated that such body armour may also increase the risk of injury due to the larger cross section presented to the blast wind.When faced with the blast and associated kinetic energy a number of factors have to be considered (i) the ability to absorb energy in crumple zones (ii) the ability to redirect that energy (iii) the level of energy that can be safely transmitted with limited injury (iv) the weight, bulk and ease of use of such solutions in the military and civilian spheres.This project builds on the research initiated by Thuy-Tien Ngoc Nguyen into the reduction of (a) pressure levels (b) impulse delivered and (c) sharpness of loading. This has been investigated using assemblies of perforated plates, varying the open area of the plate and the spacing of the plates. Parallel research has been undertaken to study the effects of granular materials with varying amounts of oils and water present as well as In all cases it was clear that the pressure level and the loading rate can be reduced in a systematic fashion. An exciting area is in the use of functionally graded foam structures which can modify the response according to the loading regime. A basis for producing and studying such systems has been developed within Imperial (ISP and partners).There is a strong clinical linkage in this project to ensure that the mitigation concepts developed reduce the injury seen by clinicians and are practical for use in field operations. The project will investigate the concepts of blast mitigation both items of clothing, body armour as well as the interiors of vehicles and buildings. The supervisors of this project have significant experience in the fundamental science of mitigation systems and in the clinical environment.
有关爆炸武器伤害的文献,在军事和恐怖场景中,表明广泛的伤害发生率,从爆炸肺到肠和其他软组织损伤。特别是,来自以色列的临床报告表明,爆炸引起的肺和肠损伤的独特性和显著死亡率。这些通常与广泛的组织撕裂感染引起的一系列附加并发症有关。原发性爆炸损伤发生率的增加是CBIS形成的主要驱动因素。在了解人体在爆炸肺区域的爆炸力和持续时间方面的极限方面取得了进展。一个合乎逻辑的延伸是首先减少这类爆炸伤害的发生率。本项目直接针对爆破缓解领域。减少初始爆炸损伤是一种明显且广泛报道的提高生存能力的明确方法。然而,虽然许多防弹衣系统能够很好地抵御弹道威胁,但研究表明,这种防弹衣也可能增加受伤的风险,因为它在冲击波中呈现出更大的横截面。当面对爆炸和相关的动能时,必须考虑许多因素(i)在褶皱区吸收能量的能力(ii)重新定向能量的能力(iii)可以在有限伤害的情况下安全传输的能量水平(iv)这种解决方案在军事和民用领域的重量、体积和易用性。该项目建立在Thuy-Tien Ngoc Nguyen发起的研究的基础上,该研究旨在降低(a)压力水平(b)传递的冲量和(c)加载的锐度。这已经研究了使用穿孔板的组件,改变板的开放面积和板的间距。同时也进行了类似的研究,以研究颗粒材料在不同数量的油和水的影响,以及在所有情况下,很明显,压力水平和加载速率可以以系统的方式降低。一个令人兴奋的领域是使用功能分级泡沫结构,它可以根据加载状态修改响应。帝国理工学院(ISP和合作伙伴)已经开发了生产和研究此类系统的基础。该项目与临床有着密切的联系,以确保制定的减轻概念减少临床医生所看到的伤害,并切实适用于实地行动。该项目将研究服装、防弹衣以及车辆和建筑物内部的防爆概念。该项目的主管在缓解系统的基础科学和临床环境方面具有丰富的经验。

项目成果

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其他文献

吉治仁志 他: "トランスジェニックマウスによるTIMP-1の線維化促進機序"最新医学. 55. 1781-1787 (2000)
Hitoshi Yoshiji 等:“转基因小鼠中 TIMP-1 的促纤维化机制”现代医学 55. 1781-1787 (2000)。
  • DOI:
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  • 影响因子:
    0
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LiDAR Implementations for Autonomous Vehicle Applications
  • DOI:
  • 发表时间:
    2021
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
生命分子工学・海洋生命工学研究室
生物分子工程/海洋生物技术实验室
  • DOI:
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  • 期刊:
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    0
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吉治仁志 他: "イラスト医学&サイエンスシリーズ血管の分子医学"羊土社(渋谷正史編). 125 (2000)
Hitoshi Yoshiji 等人:“血管医学与科学系列分子医学图解”Yodosha(涉谷正志编辑)125(2000)。
  • DOI:
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    0
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Effect of manidipine hydrochloride,a calcium antagonist,on isoproterenol-induced left ventricular hypertrophy: "Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,K.,Teragaki,M.,Iwao,H.and Yoshikawa,J." Jpn Circ J. 62(1). 47-52 (1998)
钙拮抗剂盐酸马尼地平对异丙肾上腺素引起的左心室肥厚的影响:“Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,
  • DOI:
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    0
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  • 批准号:
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Developing a 3D printed skin model using a Dextran - Collagen hydrogel to analyse the cellular and epigenetic effects of interleukin-17 inhibitors in
使用右旋糖酐-胶原蛋白水凝胶开发 3D 打印皮肤模型,以分析白细胞介素 17 抑制剂的细胞和表观遗传效应
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