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Enhanced and highly specific delivery of small interfering RNA and oligonucleotides as therapeutics for gene silencing

Enhanced and highly specific delivery of small interfering RNA and oligonucleotides as therapeutics for gene silencing
增强和高度特异性地递送小干扰 RNA 和寡核苷酸作为基因沉默的治疗剂
批准号：
nhmrc : 1054011
负责人：
Dr Simon Ting
金额：
$20.79万
依托单位：
University of Technology Sydney
依托单位国家：
澳大利亚
项目类别：
Early Career Fellowships
财政年份：
2013
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2013-01-01 至 2016-12-31
来源：
https://researchdata.edu.au/enhanced-highly-specific-gene-silencing/112361
关键词：
Enhancedhighlyspecificdeliverysmall

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英文摘要
This proposal aims to develop glyco-nanocarriers for the efficient and specific delivery of siRNA/oligonucleotides to treat liver diseases. Complex glycopolymer architectures developed here will protect desired genes from enzymatic degradation and will deliver the gene to the liver specifically for therapy, hence providing a solution towards nucleic acid therapy.
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