Enhancing the immune response to disordered malaria antigens

增强对紊乱疟疾抗原的免疫反应

• 批准号: nhmrc : 1125788
• 负责人: Dr Christopher Macraild
• 金额: $ 43.93万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/enhancing-immune-response-malaria-antigens/947665
• 关键词: Enhancing; immune; response; disordered; malaria

Half of the worlds population live at risk of malaria, and the disease kills half a million people a year, predominantly young children. Despite recent progress, a vaccine with the efficacy required to help control and ultimately eradicate malaria remains out of reach. This project studies an important class of proteins likely to form part of a future malaria vaccine, and will develop new ways to improve their effectiveness as vaccine components.

世界上一半的人口面临疟疾的威胁，这种疾病每年夺走 50 万人的生命，其中主要是幼儿。尽管最近取得了进展，但仍无法研制出具有帮助控制和最终根除疟疾所需功效的疫苗。该项目研究可能构成未来疟疾疫苗一部分的一类重要蛋白质，并将开发新方法来提高其作为疫苗成分的有效性。