Training in Engineered Biomaterials

描述(由申请人提供)：本提案旨在支持在工程生物材料跨学科领域对9-12名博士生的培训。该计划的培训机会涵盖工程学科(化学工程、材料科学工程、生物工程和电气工程)以及生物和物理科学(化学、生物学、分子生物学)的各个方面。该项目旨在通过整合材料科学、表面工程、分子生物学、纳米技术、化学、化学工程和医学，为化学工程、化学、生物工程、材料科学工程和电气工程的研究生提供跨学科教育。在这次培训中，研究生将按照个别部门的指导方针，完成基础工程、生物、数学和化学等一系列核心课程。学员还将完成生物材料工程方面的具体课程，包括分子和细胞生物工程、分子识别和设计、分子材料、生物材料以及细胞与生物材料的相互作用等课程。学生将在培训项目教员的指导下进行论文研究，该培训项目强调将工程原理应用于利用特定生物识别机制的生物材料的设计和开发。工程生物材料项目的学员将学习精确控制界面上的生物反应，阐明开启愈合和重建的生化/生物途径，并发展可实施的策略来修改生物材料和医疗设备的表面，使其能够被身体识别，并开启愈合和定义的生物反应。此外，学生将通过参加研究研讨会、期刊俱乐部和参加国家科学会议，接触到生物材料工程和相关学科的更广泛的问题。学员S的教育经验将通过获得教学经验的机会、工业实习的机会以及关于职业机会等感兴趣的问题的学生工作坊和研讨会来进一步增强。学员将在完成资格考试后从化学工程、生物工程、电气工程、化学和材料科学与工程系的高素质研究生中挑选出来，并将基于学术记录、教师推荐和对拟议研究的描述。学员将参加为期两年的培训计划。

DESCRIPTION (provided by applicant): This proposal seeks to support the training of 9-12 Ph.D. students in the interdisciplinary field of Engineered Biomaterials. The training opportunities in the program encompass aspects of the engineering disciplines (Chemical Engineering, Materials Science Engineering, Bioengineering and Electrical Engineering), and the biological and physical sciences (Chemistry, Biology, Molecular Biology). The program is designed to provide an interdisciplinary education for graduate students in Chemical Engineering, Chemistry, Bioengineering, Materials Science Engineering and Electrical Engineering by integrating materials science, surface engineering, molecular biology, nanotechnology, chemistry, chemical engineering and medicine. In this training, graduate students will complete a series of core courses in basic engineering, biology, mathematics, and chemistry in accordance with individual departmental guidelines. Trainees will also complete specific courses in biomaterials engineering including courses such as molecular and cellular bioengineering, molecular recognition and design, molecular materials, biomaterials, and cellular interactions with biomaterials. Students will conduct thesis research under the guidance of the training program faculty that emphasizes the application of engineering principals to the design and development of biomaterials that exploit specific biological recognition mechanisms. Trainees in the Engineered Biomaterials program will learn to control biological reactions at interfaces with precision, to elucidate the biochemical/biological pathways that turn on healing and reconstruction, and to evolve implementable strategies to modify the surfaces of biomaterials and medical devices so they are recognized by the body and turn on healing and defined bioreactions. In addition, students will be exposed to the broader issues in biomaterials engineering and related disciplines via participation in research seminars, journal clubs, and attendance at national scientific meetings. The trainee' s educational experience will be further enhanced by opportunities to obtain experience in teaching, opportunities for industrial intemships, and by student workshops and seminars on issues of interest such as career opportunities. Trainees will be selected from highly qualified graduate students in the departments of Chemical Engineering, Bioengineering, Electrical Engineering, Chemistry and Materials Science and Engineering following completion of the qualifying exam and will be based on academic record, faculty recommendation, and a description of proposed research. Trainees will participate in the training program for a period of 2 years.