1st International Symposium on Wound Healing and Technology (WHAT I)

第一届伤口愈合与技术国际研讨会（WHAT I）

• 批准号: 7166108
• 负责人: Buddy D Ratner
• 金额: $ 2万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-10 至 2007-07-09
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7166108
• 关键词: meeting /conference /symposium; travel; wound healing

DESCRIPTION (provided by applicant): 1st International Symposium on Wound Healing And Technology The 1st International Symposium on Wound Healing And Technology (WHAT I), August 28-30, 2006, at the University of Washington will bring together scientists, physicians and engineers from academia and industry to overview a broad spectrum of technology advances in wound healing and the barriers that remain. WHAT I is significantly different from other wound-healing conferences in that this symposium will emphasize advanced approaches to wound healing using biomaterials, controlled release, tissue engineering, and other engineering methodologies. The conference will focus on the collaboration between materials scientists, engineers, biologists, and physicians involved in laboratory and clinical research to advance wound healing technology. Also, translational research will be spotlighted with a number of company presentations and audience participation by industrial scientists. Wound healing is a significant area for discussion because researchers and scientists still lack a clear fundamental understanding of chronic wound failures, despite decades of basic research. Even when underlying mechanisms to wound-healing are understood, significant problems persist, especially with patients suffering from chronic wounds and severe burns. Tissue-engineered constructs have entered the marketplace, but the costs are high, and the benefits limited. Compromised cosmetic outcomes are unfortunately the norm. Major challenges that remain are to induce tissue regeneration and the formation of pliable, mature dermis in full-thickness wounds and to control infection. Improved biocompatibility of materials used in wound care and tissue engineering is now possible. Communication and discussion of these new ideas is central to this meeting. Another powerful technology is the controlled-release of pharmaceutical agents. To date, only one prescription drug has been approved to induce healing of chronic wounds-despite more than 15 years of R&D and investigations of numerous candidate compounds. It is widely suspected that failure to deliver an effective dose at the correct time is a major underlying deficiency of wound-healing pharmaceuticals. Thus, WHAT I will bring clinician thought-leaders, basic academic scientists, and industrial leaders together to share bold ideas and foster cross-cutting collaboration. 1st International Symposium on Wound Healing And Technology Wound healing is a critical area for discussion because we still lack a clear fundamental understanding of chronic wound failures, despite decades of basic research. In order to advance not only our knowledge, but to develop materials and technology for the market, it is imperative that materials scientists, engineers, biologists, and physicians involved in laboratory and clinical research work together. Communication and discussion of these problems and new ideas for how we can address them are central to this meeting.

描述（由申请人提供）：第一届国际伤口愈合与技术研讨会第一届国际伤口愈合与技术研讨会（WHAT I），2006年8月28日至30日，在华盛顿大学举行，将汇集来自学术界和工业界的科学家、医生和工程师，概述伤口愈合领域的广泛技术进展以及仍然存在的障碍。我是显着不同于其他伤口愈合会议，本次研讨会将强调先进的方法，伤口愈合使用生物材料，控释，组织工程，和其他工程方法。会议将重点关注材料科学家，工程师，生物学家和参与实验室和临床研究的医生之间的合作，以推进伤口愈合技术。此外，转化研究将通过一些公司的演示和工业科学家的观众参与而受到关注。伤口愈合是一个重要的讨论领域，因为研究人员和科学家仍然缺乏一个明确的基本了解慢性伤口失败，尽管几十年的基础研究。即使了解了伤口愈合的基本机制，仍然存在重大问题，特别是患有慢性伤口和严重烧伤的患者。组织工程结构已进入市场，但成本高，效益有限。不幸的是，受损的美容效果是正常的。主要的挑战仍然是在全层伤口中诱导组织再生和柔韧、成熟真皮的形成以及控制感染。现在可以改善伤口护理和组织工程中使用的材料的生物相容性。交流和讨论这些新想法是本次会议的核心。另一个强大的技术是药物制剂的控制释放。迄今为止，只有一种处方药被批准用于诱导慢性伤口愈合，尽管有超过15年的研发和许多候选化合物的研究。人们普遍怀疑，未能在正确的时间输送有效剂量是伤口愈合药物的主要潜在缺陷。因此，我将把临床思想领袖，基础学术科学家和工业领袖聚集在一起，分享大胆的想法，促进跨领域的合作。第一届伤口愈合与技术国际研讨会伤口愈合是一个关键的讨论领域，因为我们仍然缺乏一个明确的基本了解慢性伤口失败，尽管几十年的基础研究。为了不仅提高我们的知识，而且为市场开发材料和技术，参与实验室和临床研究的材料科学家，工程师，生物学家和医生必须共同努力。交流和讨论这些问题以及我们如何解决这些问题的新想法是本次会议的核心。