课题基金 / 基金详情

Context Processing and Reorganization of Spatial Coding

Context Processing and Reorganization of Spatial Coding
空间编码的上下文处理和重组
批准号：
6585382
负责人：
David M. Smith
金额：
$3.83万
依托单位：
UNIVERSITY OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
2002
资助国家：
美国
项目状态：
已结题
起止时间：
2002-09-28 至 2005-07-31
来源：
https://reporter.nih.gov/project-details/6585382
关键词：
behavior test behavioral /social science research tag cognition hippocampus laboratory rat learning limbic system memory neural information processing neural plasticity neuroanatomy neurons neuropharmacology postdoctoral investigator psychobiology psychopharmacology single cell analysis thalamus

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英文摘要
DESCRIPTION (provided by applicant): The proposed research examines the learning and memory functions of limbic brain circuitry involving the hippocampus, retrosplenial cortex, and the anterior and lateral dorsal thalamus. Pathology in these regions has been associated with the human cognitive impairments seen in amnesic syndromes and Alzheimer's disease. The specific goal is to examine the contributions these regions make to contextual learning. It is proposed that these regions function cooperatively to encode the cognitive and behavioral features of a learning context and thereby provide a basis for determining appropriate behaviors in different learning situations. To assess this, multi-site neuronal recording and temporary inactivation techniques will be employed while rats learn to obtain food rewards in two different learning contexts.
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Hippocampus, Retrosplenial Cortex and Contextual Learning and Memory
  • 批准号：
    10326364
  • 项目类别：
  • 资助金额：
    $40.85万
  • 财政年份：
    2009
  • 负责人：
    David M. Smith
  • 依托单位：
    CORNELL UNIVERSITY
Hippocampus, Posterior Cingulate Cortex and Contextual Learning and Memory
  • 批准号：
    7785394
  • 项目类别：
  • 资助金额：
    $33.85万
  • 财政年份：
    2009
  • 负责人：
    David M. Smith
  • 依托单位：
    CORNELL UNIVERSITY
Hippocampus, Posterior Cingulate Cortex and Contextual Learning and Memory
  • 批准号：
    8388808
  • 项目类别：
  • 资助金额：
    $30.22万
  • 财政年份：
    2009
  • 负责人：
    David M. Smith
  • 依托单位：
    CORNELL UNIVERSITY
Hippocampus, Posterior Cingulate Cortex and Contextual Learning and Memory
  • 批准号：
    8204478
  • 项目类别：
  • 资助金额：
    $31.48万
  • 财政年份：
    2009
  • 负责人：
    David M. Smith
  • 依托单位：
    CORNELL UNIVERSITY