EARLY ADVERSE LIFE EVENTS AND MAJOR DEPRESSION

早期不良生活事件和严重抑郁症

• 批准号: 6565729
• 负责人: CHARLES B NEMEROFF
• 金额: $ 29.31万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-12-01 至 2002-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6565729
• 关键词: antidepressants; child abuse; clinical research; early experience; fluoxetine; human subject; human therapy evaluation; major depression; mental disorder chemotherapy; psychological stressor; stress

The goal of this study is to determine whether fluoxetine (antidepressant) reverses the neurobiological consequences of early life stress (e.g., child abuse) and, thus, is effective for treatment and prevention of stress-related syndromal or subsyndromal psychopathology.

本研究的目的是确定氟西汀（抗抑郁药）是否能逆转早期生活压力（如虐待儿童）的神经生物学后果，从而有效地治疗和预防与压力相关的综合征或亚综合征性精神病理学。