Environmental risk factors for iron overload-related disease in a cohort study of hereditary haemochromatosis

遗传性血色病队列研究中铁超载相关疾病的环境危险因素

• 批准号: nhmrc : 628697
• 负责人: A/Pr Lyle Gurrin
• 金额: $ 10.2万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/environmental-risk-factors-hereditary-haemochromatosis/95350
• 关键词: Environmental; risk; factors; iron; overload

Results published last year from our Melbourne HealthIron study of hereditary haemochromatosis (iron overload disease) show that almost one third of the 50,000 men genetically at risk of iron overload in Australia will develop symptoms of disease including fatigue, arthritis and liver damage. We will use data from the recent follow-up of the Health2020 cohort, of which HealthIron is a sub-study, to determine environmental risk factors for progression to disease in people with iron overload.

我们的墨尔本HealthIron对遗传性血色病（铁超载疾病）的研究去年发表的结果显示，在澳大利亚有铁超载风险的5万名男性中，近三分之一将出现疾病症状，包括疲劳，关节炎和肝损伤。我们将使用Health2020队列的近期随访数据，其中HealthIron是一项子研究，以确定铁超载患者疾病进展的环境风险因素。