Novel genetic and environmental modifiers of the risk of iron overload-related disease in HFE-associated hereditary haemochromatosis in cohort of middle-aged Australians
Novel genetic and environmental modifiers of the risk of iron overload-related disease in HFE-associated hereditary haemochromatosis in cohort of middle-aged Australians
批准号:
nhmrc : 1032598
负责人:
A/Pr Lyle Gurrin
金额:
$30.12万
依托单位国家:
澳大利亚
项目类别:
Career Development Fellowships
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2015-12-31
中文摘要
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英文摘要
People who carry mutations in the HFE gene are pre-disposed to body iron overload but not all of them developed subsequent disease. According to the investigators of the “HealthIron” study in Melbourne, only 28% of men and 1% of women with faulty HFE genes go on to develop disease. This study has recruited more than 1,000 people from the community, and will determine which environmental and genetic risk factors stop people with iron overload from getting symptoms of disease.
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