A Device for Selecting and Rejecting X-ray Harmonics

一种X射线谐波选择和剔除装置

• 批准号: 6642477
• 负责人: CAHIT KARANFIL
• 金额: $ 12.5万
• 依托单位: QUERCUS TECHNOLOGIES
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-05-05 至 2004-12-01
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6642477
• 关键词: X ray crystallography; X ray spectrometry; bioimaging /biomedical imaging; biomedical equipment development; electromagnetic radiation; physical process; silicon; structural biology; synchrotrons

DESCRIPTION (provided by applicant): Synchrotron radiation is an important tool for structural biological studies using X-ray diffraction, X-ray scattering, and X-ray absorption spectroscopy. The quality of data often depends critically on beam spectral quality. The technical limitations (e.g. energy range) of beamlines can make or break experiments. In this application we propose to optimize, design, construct, and test over a wide range of energies a novel, inexpensive, easy to align device ("beam cleaner"). The device has several benefits: improving X-ray beam spectral quality; extending (e.g. tripling) the useful energy range of existing beamlines at third generation synchrotron radiation sources by selecting specific harmonics for experimental use; passively compensating for vertical beam motion as the monochromator angle is changed; and focussing the beam. Beam cleaners offer the potential to simplify new beamline designs by permitting use of channel-cut monochromators in vacuum, followed by a beam cleaner arranged so as to passively compensate for vertical beam motion, without the need for precise in-vacuum mechanics. This device also potentially can be used as a non-beam-hardening variable attenuator for experiments on radiation sensitive biological samples at intense third generation sources, and the devices also appear to be applicable to laboratory research.

描述（由申请人提供）： 同步辐射是利用 X 射线衍射、X 射线散射和 X 射线吸收光谱进行结构生物学研究的重要工具。数据质量通常很大程度上取决于光束光谱质量。光束线的技术限制（例如能量范围）可能会决定实验的成败。 在此应用中，我们建议在广泛的能量范围内优化、设计、构造和测试一种新颖、廉价、易于对准的设备（“光束清洁器”）。该设备有几个好处： 提高 X 射线束光谱质量；通过选择用于实验的特定谐波，扩展（例如三倍）第三代同步加速器辐射源现有束线的有用能量范围；当单色仪角度改变时，被动补偿垂直光束运动；并聚焦光束。光束清洁器允许在真空中使用通道切割单色仪，然后布置光束清洁器以被动补偿垂直光束运动，而不需要精确的真空机械装置，从而提供了简化新光束线设计的潜力。该设备还有可能用作非光束硬化可变衰减器，用于在强第三代源下对辐射敏感的生物样品进行实验，并且该设备似乎也适用于实验室研究。