Core--High throughput genotyping

核心--高通量基因分型

• 批准号: 6575688
• 负责人: ROBERT C MILLIKAN
• 金额: $ 7.35万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-01 至 2003-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6575688
• 关键词: biomedical facility; environmental health; genotype; high throughput technology

The UNC High Throughput Genotyping Core Facility was established in 1998 as a joint collaboration of the UNC Lineberger Comprehensive Cancer Center and the School of Public Health. The original goal of the Core Facility was to conduct high-speed genotyping assays in support of epidemiologic and clinical studies of cancer. In this case, the investigators propose to increase the capacity of the facility by increasing the number of genotyping assays performed, and to expand the focus of the facility to include non-cancer outcomes. The aims of the Core are to: 1) to make available to NIEHS Center members the services provided by the UNC High Throughput Genotyping Core Facility; 2) to increase the capacity of the High Throughput Genotyping Core Facility in order to meet the needs of NIEHS Center investigators; and, 3) to enlarge the scope of genotyping assays conducted by the Core to include markers of susceptibility to non-cancer outcomes, including reproductive health, cardiovascular disease and neurologic disease and development.

1998年成立的高通量基因分型核心设施， 联合合作的莱恩斯伯格综合癌症中心和 公共卫生学院。核心基金的最初目标是 进行高速基因分型检测，以支持流行病学和临床 癌症的研究。在这种情况下，调查人员建议增加 通过增加基因分型检测的数量来提高设施的能力 进行，并扩大设施的重点，包括非癌症 结果。核心的目标是：1）提供给NIEHS中心 成员提供的服务，由联合国人权事务高级专员办事处基因分型核心 设施; 2）增加高通量基因分型核心的容量 设施，以满足NIEHS中心研究者的需求;以及，3） 扩大由核心进行的基因分型检测的范围，以包括 对非癌症结局的易感性标志物，包括生殖 健康、心血管疾病和神经系统疾病与发育。