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Core--High throughput genotyping

Core--High throughput genotyping
核心--高通量基因分型
批准号:
6575688
负责人:
ROBERT C MILLIKAN
金额:
$7.35万
依托单位国家:
美国
项目类别:
财政年份:
2002
资助国家:
美国
项目状态:
已结题
起止时间:
2002-04-01 至 2003-03-31

项目摘要

项目成果

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中文摘要
翻译
北卡罗来纳大学高通量基因分型核心设施成立于1998年,是一个 北卡罗来纳大学莱恩伯格综合癌症中心和 公共卫生学院。核心基金的最初目标是 进行高速基因分型分析,以支持流行病学和临床 癌症研究。在这种情况下,调查人员建议增加 通过增加基因分型分析的数量来提高设施的能力 实施,并扩大设施的重点,包括非癌症 结果。核心的目标是:1)向NIEHS中心提供 成员由北卡罗来纳大学高通量基因分型核心提供的服务 设施;2)增加高通量基因分型核心的容量 设施,以满足NIEHS中心调查人员的需求;以及,3) 扩大核心进行的基因分型分析的范围,以包括 对包括生殖在内的非癌症结果的易感性标志 健康、心血管疾病和神经疾病与发展。
英文摘要
The UNC High Throughput Genotyping Core Facility was established in 1998 as a joint collaboration of the UNC Lineberger Comprehensive Cancer Center and the School of Public Health. The original goal of the Core Facility was to conduct high-speed genotyping assays in support of epidemiologic and clinical studies of cancer. In this case, the investigators propose to increase the capacity of the facility by increasing the number of genotyping assays performed, and to expand the focus of the facility to include non-cancer outcomes. The aims of the Core are to: 1) to make available to NIEHS Center members the services provided by the UNC High Throughput Genotyping Core Facility; 2) to increase the capacity of the High Throughput Genotyping Core Facility in order to meet the needs of NIEHS Center investigators; and, 3) to enlarge the scope of genotyping assays conducted by the Core to include markers of susceptibility to non-cancer outcomes, including reproductive health, cardiovascular disease and neurologic disease and development.
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Genetic Susceptibility for Breast Cancer Subtypes
Large-scale haplotyping for breast cancer susceptibility in Afric. Amer. and Wh.
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CORE-- Molecular Epidemiology
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