CORE--TECHNICAL COMPONENT

描述：（申请人描述）核心的主要贡献是运行、维护和发展放射研究加速器设施（RARAF），以便为生物项目提供适当能量、适当剂量和剂量率的α粒子。RARAF的经理（Steve Marino）与生物学家合作，确保适当的辐照方案和正确的剂量测定。核心还为订购设备和用品以及维护帐户提供了一个行政框架。生物仪器（机器）车间是设计和制造复杂的计算机控制辐照设备和单粒子束流线的关键。最后但并非最不重要的是，核心提供了交换信息和思想的工具，并协调出版数据。组织结构由执行委员会和外部咨询委员会组成，旨在最大限度地发挥综合努力的协同作用，以实现该计划项目的目标。

DESCRIPTION: (Applicant's Description) The essential contribution of the Core is the operation, maintenance and development of the Radiological Research Accelerator Facility (RARAF), so that alpha-particles of appropriate energy, at the appropriate dose and dose-rate, are available for the biological projects. The manger of RARAF (Steve Marino) collaborates with the biologists to ensure appropriate irradiation protocols and correct dosimetry. The Core also provides an administrative framework for the ordering of equipment and supplies and the maintenance for accounts. The Bio- Instrument (machine) Shop is a vital need to design and fabricate sophisticated computer-controlled irradiation facility and single-particle beam line. Last but not least, the core presents a vehicle for the exchange of information and ideas, and to coordinate data for publication. The organization structure, consisting of an executive committee and an external advisory committee, is designed to maximize the level of synergy in an integrated effort to accomplish the goals of this program project.