Clinical Development Research Career Development Program

描述（由申请人提供）：这是一份支持达纳-法伯/哈佛癌症中心临床癌症研究中最多五名高级研究员或初级教师职业发展的提案，该中心是由哈佛医学院（HMS）、哈佛公共卫生学院和HMS主要教学医院组成的联盟--达纳-法伯癌症研究所， 马萨诸塞州总医院布里格姆妇女医院医院，儿童？医院和贝斯以色列女执事医院。这项建议的目的是解决医生科学家的需要，能够将分子遗传学和生物学，药物发现，流行病学和心理社会研究的最有前途的发现转化为癌症患者的有用应用。我们建议在外科、放射、儿科、内科和护理肿瘤学的子专业中选择五名高级研究员、讲师或助理教授级别的医生或护士，最多提供五年的支持。他们的职业发展计划将包括临床试验设计和管理的教学课程工作，以及与他们感兴趣的领域相关的重要技术的正式实践培训 作为临床试验的指导研究。候选人可以追求与临床试验相关的实验室培训，如遗传学，药代动力学或临床免疫学，作为其职业发展计划的一部分。每个候选人将设计和管理一个临床研究试验， 他/她的赠款支持的努力。将鼓励妇女和少数民族候选人申请该奖项。候选人实验室、临床和生物统计方面的导师？的工作将是培训计划的一个组成部分。一个由来自主要癌症专业、基础科学、流行病学和生物统计学的教师组成的咨询委员会将选择 候选人，监督他们的进步，并评估他们的培训，研究和指导的有效性。咨询委员会还将负责评估该计划的整体有效性，并确定新的重点领域的机会。

DESCRIPTION (provided by applicant): This is a proposal to support career development for up to five senior fellows or junior faculty members in clinical cancer research at the Dana-Farber/Harvard Cancer Center, a consortium of Harvard Medical School (HMS), Harvard School of Public Health, and the primary HMS teaching hospitals -- Dana-Farber Cancer Institute, Massachusetts General Hospital, Brigham and Women?s Hospital, The Children?s Hospital and Beth Israel Deaconess Hospital. The aim of this proposal is to address the need for physician scientists capable of translating the most promising discoveries of molecular genetics and biology, drug discovery, epidemiology, and psychosocial research into useful application in cancer patients. We propose to select five physicians or nurses at the level of Senior Research Fellow, Instructor or Assistant Professor in subspecialties of surgical, radiation, pediatric, medical, and nursing oncology, for a maximum of five years of support. Their career development plan will include didactic course work in clinical trial design and management, and formal hands-on training in important technologies related to their field of interest, as well as mentored research involving clinical trials. Candidates may pursue laboratory training related to clinical trials, such as genetics, pharmacokinetics, or clinical immunology as part of their career development plan. Each candidate will design and manage a clinical research trial as part of his/her grant-supported effort. Women and minority candidates will be encouraged to apply for this award. Mentors for the laboratory, clinical, and biostatistical aspects of the candidate?s work will be an integral part of the training plan. An advisory committee of faculty drawn from the major cancer specialties, basic science, epidemiology, and biostatistics will select candidates, supervise their progress, and evaluate the effectiveness of their training, research, and mentoring. The advisory committee will also be responsible for evaluating the overall effectiveness of the program and identifying opportunities for new areas of emphasis.