ANGER AND PARENT-TO-CHILD AGGRESSION

这是修订后的临床科学家导师发展奖 描述相关培训和研究计划的应用程序 和治疗父母对孩子的攻击性 虐待他们的孩子。候选人的目标是获得所需的培训 进行心理治疗和综合治疗的对照试验 旨在减少亲子关系的心理药理学干预 攻击性。这一目标将通过拟议的研究和 通过由自主学习组成的教育计划，课程在 统计和研究设计，以及与虐待家庭的临床工作。 由于儿童身体虐待(CPA)涉及父母对儿童的攻击， 丰富的关于其他背景下的攻击性的文献可以用来更好地 了解注册会计师。这项拟议的研究由以下发现提供信息：愤怒 导致攻击性行为，高水平的人与低水平的人相比 愤怒表现出更多的攻击性行为，而5-羟色胺能抗抑郁药，如 氟西汀可以减少愤怒和攻击性。这种随机双盲安慰剂 对照研究将检查氟西汀是否添加到标准治疗中 社区中身体虐待的父母，通过检查 氟西汀减少被分配给氟西汀的虐待父母的攻击性 加常规治疗(TAU)或安慰剂加TAU。父母的因果关系模型 攻击性也将被考察。具体地说，愤怒的作用将是 作为以下变量的影响的中介者被检查 注册会计师：精神病理学(抑郁和焦虑)、社会认知、生理学 唤醒、冲动和选定的生态因素。八十个施虐者 将对家长进行研究。与认知行为疗法相比，氟西汀 可以通过降低愤怒情绪的强度来减少攻击性 随之而来的觉醒和攻击性行为倾向。因此，如果氟西汀降低 父母的攻击性，可能会被证明是心理治疗的有用辅助工具 目前用于治疗CPA的干预措施。虐待父母的先期研究 我没有在单个样本中检查过这些变量，并且没有 在这一组中进行抗抑郁药物的试验。这个应用程序结合了 在因果和治疗研究方面的培训和经验，可能有助于 对儿童身体虐待的理解和处理。

This is a revised Mentored Clinical Scientist Development Award application that describes a program of training and research on the correlates and treatment of parent-to-child aggression in parents who have physically abused their child. The candidate's goal is to acquire the training needed to conduct controlled trials of integrated psychotherapeutic and psychopharmacologic interventions designed to reduce parent-to-child aggression. This goal is to be achieved through the proposed research and through the educational plan consisting of independent study, courses in statistics and research design, and clinical work with abusive families. Because child physical abuse (CPA) involves parent-to-child aggression, the wealth of literature on aggression in other settings can be used to better understand CPA. The proposed study is informed by the following findings: anger contributes to aggressive behavior, persons with high compared to low levels of anger show more aggressive behavior, and serotonergic antidepressants such as fluoxetine reduce anger and aggression. This randomized double-blind placebo controlled study will examine whether fluoxetine adds to standard treatment for physically abusive parents in the community, by examining the effectiveness of fluoxetine in reducing aggression among abusive parents assigned to Fluoxetine plus Treatment-as-Usual (TAU) or Placebo plus TAU. A causal model of parental aggression will also be examined. Specifically, the role of anger will be examined as a mediator of the effects of the following variables implicated in CPA: psychopathology (depression and anxiety), social cognition, physiologic arousability, impulsivity and selected ecological factors. Eighty abusive parents will be studied. In contrast to cognitive-behavior therapy, fluoxetine may reduce aggression through reducing the intensity of angry emotion and its attendant arousal and aggressive action tendencies. Thus, if fluoxetine reduces parental aggression, it may prove to be a useful adjunct to psychotherapeutic interventions currently used to treat CPA. Prior studies of abusive parents have not examined these variables within a single sample and there are no trials of antidepressants in this group. This application, which combines training and experience in causal and treatment research, may contribute to the understanding and treatment of child physical abuse.