ANGER AND PARENT-TO-CHILD AGGRESSION

这是一个修订后的指导临床科学家发展奖 一种应用程序，描述了相关的培训和研究计划 和治疗父母对孩子的攻击， 虐待他们的孩子候选人的目标是获得所需的培训， 进行综合心理治疗的对照试验， 旨在减少父母对孩子的心理药理学干预 侵略这一目标将通过拟议的研究和 通过教育计划，包括独立学习， 统计和研究设计，以及对虐待家庭的临床工作。 由于儿童身体虐待（CPA）涉及父母对儿童的攻击， 丰富的关于其他环境中的攻击性的文献可以用来更好地 了解CPA这项拟议中的研究得到了以下发现的启发：愤怒 有助于攻击性行为，与低水平相比，高水平的人 愤怒表现出更多的攻击性行为， 氟西汀减少愤怒和攻击性。这个随机双盲安慰剂 对照研究将检查氟西汀是否增加了标准治疗， 在社区的身体虐待的父母，通过检查的有效性， 氟西汀在减少分配给氟西汀的虐待父母中的攻击性 加按剂量治疗（TAU）或安慰剂加TAU。父母的因果模型 还将审查侵略行为。具体来说，愤怒的作用将是 作为涉及以下变量的影响的调解人进行了检查， CPA：精神病理学（抑郁和焦虑），社会认知，生理 唤醒性、冲动性和选定的生态因素。80虐待 父母会被研究。与认知行为疗法相比，氟西汀 可以通过降低愤怒情绪的强度来减少攻击性， 随之而来的觉醒和攻击性行为倾向。因此，如果氟西汀减少 父母的攻击，它可能被证明是一个有用的辅助心理治疗 目前用于治疗CPA的干预措施。先前对虐待父母的研究 我没有在一个单一的样本中检查这些变量， 抗抑郁药的临床试验该应用程序结合了 在因果关系和治疗研究方面的培训和经验，可能有助于 对儿童身体虐待的理解和处理。

This is a revised Mentored Clinical Scientist Development Award application that describes a program of training and research on the correlates and treatment of parent-to-child aggression in parents who have physically abused their child. The candidate's goal is to acquire the training needed to conduct controlled trials of integrated psychotherapeutic and psychopharmacologic interventions designed to reduce parent-to-child aggression. This goal is to be achieved through the proposed research and through the educational plan consisting of independent study, courses in statistics and research design, and clinical work with abusive families. Because child physical abuse (CPA) involves parent-to-child aggression, the wealth of literature on aggression in other settings can be used to better understand CPA. The proposed study is informed by the following findings: anger contributes to aggressive behavior, persons with high compared to low levels of anger show more aggressive behavior, and serotonergic antidepressants such as fluoxetine reduce anger and aggression. This randomized double-blind placebo controlled study will examine whether fluoxetine adds to standard treatment for physically abusive parents in the community, by examining the effectiveness of fluoxetine in reducing aggression among abusive parents assigned to Fluoxetine plus Treatment-as-Usual (TAU) or Placebo plus TAU. A causal model of parental aggression will also be examined. Specifically, the role of anger will be examined as a mediator of the effects of the following variables implicated in CPA: psychopathology (depression and anxiety), social cognition, physiologic arousability, impulsivity and selected ecological factors. Eighty abusive parents will be studied. In contrast to cognitive-behavior therapy, fluoxetine may reduce aggression through reducing the intensity of angry emotion and its attendant arousal and aggressive action tendencies. Thus, if fluoxetine reduces parental aggression, it may prove to be a useful adjunct to psychotherapeutic interventions currently used to treat CPA. Prior studies of abusive parents have not examined these variables within a single sample and there are no trials of antidepressants in this group. This application, which combines training and experience in causal and treatment research, may contribute to the understanding and treatment of child physical abuse.