COMMUNITY SURVEILLANCE OF CARDIOVASCULAR DISEASE--RISK F

心血管疾病的社区监测——风险 F

• 批准号: 6637441
• 负责人: Russell V Luepker
• 金额: $ 29.51万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 1979
• 资助国家: 美国
• 起止时间: 1979-04-01 至 2005-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6637441
• 关键词: adolescence (12-20); adult human (21+); blood chemistry; blood lipid; cardiovascular disorder; cardiovascular disorder epidemiology; cardiovascular disorder prevention; clinical research; community health services; disease /disorder proneness /risk; gender difference; health behavior; human morbidity; human mortality; human subject; longitudinal human study; middle childhood (6-11); nutrition related tag; patient /disease registry; racial /ethnic difference; tobacco abuse; weight control

Data from the most recent survey (1995-97) of the Minnesota Heart Survey (MHS) indicate that previously favorable trends in cardiovascular risk factor levels are attenuating. While cigarette smoking and self-reported dietary fat intake continued to decline, mean body weight rose substantially and rapidly, physical activity decreased, and the previous decline in serum total cholesterol was no longer apparent. These trends may or may not continue in the future. As part of the Minnesota Heart Survey, we propose to conduct another population survey of 4,000 adults, ages 25-84 years in 2000-02, to detect current trends in cardiovascular disease risk factors, including serum lipids, blood pressure, cigarette smoking prevalence, dietary fat intake, obesity, diabetes, physical inactivity, fibrinogen, and serum vitamin E. The proposed survey will build upon four previous, independent cross-sectional surveys conducted in 1980-82, 1985-87, 1990-92, and 1995-97, which collectively examined 23,000 adults in the metropolitan Minneapolis-St. Paul (2.3 million residents in 1990). Using a sampling strategy identical to that of prior surveys, households will be randomly selected by a two-stage cluster design. A wide range of risk factors for cardiovascular disease will be measured using previously employed methods. Cohort and ecological analyses will link secular trends in risk factors to morbidity and mortality from coronary heart disease, congestive heart failure, and stroke within the same population. To estimate risk factor levels in children and adolescents, 1,000 youth ages 8-17, offspring of selected adults, will also be recruited and examined using youth-specific measurement instruments where appropriate (e.g., physical activity and smoking). New methodological studies are proposed to understand trends in reported dietary intake which are irreconcilable with trends in body weight and serum cholesterol. New information will be collected on measures of leisure time physical inactivity and diet validation. Serial ascertainment of risk factor levels in populations is crucial to understanding, predicting, and controlling population trends in cardiovascular disease. The Minnesota Heart Survey has been, and continues to offer, a powerful resource to examine long-term trends in cardiovascular disease risk factors.

明尼苏达心脏调查（MHS）最近的调查（1995-97）数据表明，心血管危险因素水平的先前有利趋势正在减弱。 虽然吸烟和自我报告的膳食脂肪摄入量继续下降，平均体重大幅迅速上升，体力活动减少，血清总胆固醇先前的下降不再明显。 这些趋势在未来可能会继续，也可能不会继续。作为明尼苏达心脏调查的一部分，我们建议在2000- 2002年对4,000名年龄在25-84岁之间的成年人进行另一项人口调查，以检测心血管疾病危险因素的当前趋势，包括血脂、血压、吸烟率、膳食脂肪摄入、肥胖、糖尿病、缺乏运动、纤维蛋白原和血清维生素E。拟议的调查将建立在1980- 1982年、1985- 1987年、1990- 1992年和1995- 1997年进行的四次独立横断面调查的基础上，这些调查共调查了明尼阿波利斯-圣保罗大都市的23，000名成年人（1990年为230万居民）。 调查采用与以往统计调查相同的抽样策略，以两阶段的群组设计随机抽取住户。 将使用以前采用的方法测量心血管疾病的各种风险因素。队列和生态学分析将在同一人群中将危险因素的长期趋势与冠心病、充血性心力衰竭和中风的发病率和死亡率联系起来。 为了估计儿童和青少年的风险因素水平，还将招募1,000名8-17岁的青少年，他们是选定的成年人的后代，并酌情使用针对青少年的测量工具进行检查（例如，身体活动和吸烟）。 提出了新的方法学研究，以了解报告的饮食摄入量的趋势与体重和血清胆固醇的趋势不一致。 将收集关于闲暇时间、身体不活动和饮食验证措施的新信息。人群中危险因素水平的系列确定对于理解、预测和控制心血管疾病的人群趋势至关重要。 明尼苏达州心脏调查一直是并将继续提供一个强大的资源，以检查心血管疾病危险因素的长期趋势。