Scholar Development Clinical Research (RMI)

学者发展临床研究（RMI）

• 批准号: 7292669
• 负责人: Russell V Luepker
• 金额: $ 318.65万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-23 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7292669
• 关键词: Classification; Clinic; Clinical; Clinical Research; Clinical Trials; Collaborations; County Hospitals; Development; Discipline; Discipline of Nursing; Disease; Epidemiology; Faculty; Funding; General Population; Goals; Grant; Health; Human; Industry; Institution; International; Investments; Knowledge; Laboratories; Leadership; Medicine; Mentored Clinical Scientist Development Program; Mentors; Minnesota; Minority; Nature; Outcomes Research; Persons; Pharmacologic Substance; Pharmacy facility; Population; Population Heterogeneity; Postdoctoral Fellow; Productivity; Public Health; Recording of previous events; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Resources; SECTM1 gene; School Dentistry; Schools; Strategic Planning; Students; Support Groups; Training; Training Programs; Translating; United States Department of Veterans Affairs; United States National Institutes of Health; Universities; Work; career; experience; improved; medical specialties; multidisciplinary; programs

Dramatic increases in the knowledge of basic disease mechanisms from the laboratory are slow to find the bedside, clinic or general population. These delays are due,in part, to a lack of enough well-trained clinical researchers to translate scientific discoveries in human populations. Recognizing this deficit, the University of Minnesota and its Academic Health Center (AHC) developed a strategic plan in 2003 prioritizing clinical research (CR) at all University levels from undergraduates to the senior faculty. The proposed K12 program fits well into those plans and will enhance the substantial Minnesota CR investment. This K12 proposal embraces the spectrum of CR from observational epidemiology to clinical trials to outcomes research. Recognizing the multidisciplinary nature of CR, we include the Schools of Dentistry, Medicine, Nursing, Pharmacy and Public Health in CR scholar identification, training and development. These disciplines have a history of working together to provide leadership for CR. Beginning with clinical specialty fellows, postdoctoral students and junior faculty, we will select CR scholars to participate in current and new coursework from an ongoing K30 grant. Advised by three-person multidisciplinary mentor teams, including a biostatistician, the scholars will access substantial resources and infrastructure in the AHC including: 1) Skilled, experienced and enthusiastic senior mentors; 2) Biostatisticians with an international reputation for CR; 3) A General Clinical Research Center (GCRC) with a 25-year record of productivity; 4) A pharmaceutical center; 5) Veterans Administration and Hennepin County hospitals with diverse populations; 6) A minority recruitment program; 7) A substantial portfolio of federal and industry funded CR projects,and; 8) A proposed Shared Clinical Research Support Group. There is a history of collaboration among AHC schools in multidisciplinary CR using a team approach. This proposal expands on a successful CR enterprise in an institution with a ten-year strategic investment plan. The goal is to improve health and cure diseases through CR. This proposal merges many University of Minnesota strengths in a systematic, focused career development training program for NIH CR scholars.

从实验室获得的关于基本疾病机制的知识急剧增加，但发现疾病的速度却很慢