Scholar Development Clinical Research (RMI)

学者发展临床研究（RMI）

• 批准号: 7493462
• 负责人: Russell V Luepker
• 金额: $ 363.96万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-23 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7493462
• 关键词: Classification; Clinic; Clinical; Clinical Research; Clinical Trials; Collaborations; County Hospitals; Development; Discipline; Discipline of Nursing; Disease; Epidemiology; Faculty; Funding; General Population; Goals; Grant; Health; Human; Industry; Institution; International; Investments; Knowledge; Laboratories; Leadership; Medicine; Mentored Clinical Scientist Development Program; Mentors; Minnesota; Minority; Nature; Outcomes Research; Persons; Pharmacologic Substance; Pharmacy facility; Population; Population Heterogeneity; Postdoctoral Fellow; Productivity; Public Health; Recording of previous events; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Resources; SECTM1 gene; School Dentistry; Schools; Strategic Planning; Students; Support Groups; Training; Training Programs; Translating; United States Department of Veterans Affairs; United States National Institutes of Health; Universities; Work; career; experience; improved; medical specialties; multidisciplinary; programs

Dramatic increases in the knowledge of basic disease mechanisms from the laboratory are slow to find the bedside, clinic or general population. These delays are due,in part, to a lack of enough well-trained clinical researchers to translate scientific discoveries in human populations. Recognizing this deficit, the University of Minnesota and its Academic Health Center (AHC) developed a strategic plan in 2003 prioritizing clinical research (CR) at all University levels from undergraduates to the senior faculty. The proposed K12 program fits well into those plans and will enhance the substantial Minnesota CR investment. This K12 proposal embraces the spectrum of CR from observational epidemiology to clinical trials to outcomes research. Recognizing the multidisciplinary nature of CR, we include the Schools of Dentistry, Medicine, Nursing, Pharmacy and Public Health in CR scholar identification, training and development. These disciplines have a history of working together to provide leadership for CR. Beginning with clinical specialty fellows, postdoctoral students and junior faculty, we will select CR scholars to participate in current and new coursework from an ongoing K30 grant. Advised by three-person multidisciplinary mentor teams, including a biostatistician, the scholars will access substantial resources and infrastructure in the AHC including: 1) Skilled, experienced and enthusiastic senior mentors; 2) Biostatisticians with an international reputation for CR; 3) A General Clinical Research Center (GCRC) with a 25-year record of productivity; 4) A pharmaceutical center; 5) Veterans Administration and Hennepin County hospitals with diverse populations; 6) A minority recruitment program; 7) A substantial portfolio of federal and industry funded CR projects,and; 8) A proposed Shared Clinical Research Support Group. There is a history of collaboration among AHC schools in multidisciplinary CR using a team approach. This proposal expands on a successful CR enterprise in an institution with a ten-year strategic investment plan. The goal is to improve health and cure diseases through CR. This proposal merges many University of Minnesota strengths in a systematic, focused career development training program for NIH CR scholars.

从实验室获得的基本疾病机制的知识急剧增加， 床旁、诊所或一般人群。这些延误的部分原因是缺乏足够的训练有素的临床医生， 研究人员将科学发现转化为人类。认识到这一不足，大学 明尼苏达州及其学术健康中心（AHC）于2003年制定了战略计划，优先考虑临床 研究（CR）在所有大学水平从本科生到高级教师。K12计划 该项目非常符合这些计划，并将加强明尼苏达州的CR投资。 该K12提案涵盖了从观察性流行病学到临床试验的CR范围， 成果研究。认识到CR的多学科性质，我们包括牙科学校， 医学，护理，药学和公共卫生在CR学者识别，培训和发展。 这些学科有着共同努力为CR提供领导的历史。从临床开始 专业研究员，博士后学生和初级教师，我们将选择CR学者参加目前的 以及正在进行的K30资助的新课程。由三人多学科导师团队提供建议， 包括一名生物统计学家在内，这些学者将获得AHC的大量资源和基础设施 包括：1）熟练、经验丰富、热情的高级导师; 2）具有国际 CR的声誉; 3）具有25年生产力记录的综合临床研究中心（GCRC）; 4）A 5）退伍军人管理局和Hennepin县医院与不同的人口; 6)少数族裔招募计划; 7）联邦和行业资助的CR项目的实质性组合，以及; 8)拟议的共享临床研究支持小组。 AHC学校在多学科CR中使用团队方法进行合作的历史。这 该提案扩展了一家拥有十年战略投资计划的机构中成功的CR企业。 我们的目标是通过CR改善健康和治疗疾病。这一建议将许多大学合并， 明尼苏达州的优势是为NIH CR学者提供系统的，有重点的职业发展培训计划。