Scholar Development Clinical Research (RMI)

实验室对基本疾病机制的知识急剧增加，却迟迟没有发现 床边、诊所或普通人群。这些延误的部分原因是缺乏足够训练有素的临床医生。 研究人员将科学发现转化为人类群体。认识到这一缺陷，该大学 明尼苏达大学及其学术健康中心(AHC)在2003年制定了一项战略计划，优先考虑临床 从本科生到高级教员的所有大学级别的研究(CR)。拟议的K12计划 很好地符合这些计划，并将加强明尼苏达州的大量CR投资。 这份K12提案涵盖了从观察流行病学到临床试验的CR范围，以 结果研究。认识到CR的跨学科性质，我们包括牙科学校， 医学、护理学、药剂学和公共卫生专业的CR学者的鉴定、培训和发展。 这些学科有共同努力为CR提供领导力的历史。从临床开始 专业研究员、博士后和初级教职员工，我们将挑选CR学者参加本次 和正在进行的K30拨款的新课程作业。由三人多学科导师团队提供建议， 包括一名生物统计学家在内，这些学者将获得AHC的大量资源和基础设施 包括：1)技术熟练、经验丰富、热情的高级导师；2)拥有国际 CR的声誉；3)具有25年生产力记录的综合临床研究中心(GCRC)；4)A 5)不同人群的退伍军人管理局和亨内平县医院； 6)少数族裔招募计划；7)大量联邦和行业资助的CR项目组合，以及； 8)拟议的共享临床研究支持小组。 AHC学校之间在使用团队方法进行多学科合作方面有过合作的历史。这 Proposal扩展了一个机构中成功的CR企业，并制定了十年战略投资计划。 其目标是通过CR改善健康和治疗疾病。这项提议合并了多所大学 明尼苏达州在为NIH CR学者提供系统的、有重点的职业发展培训计划方面具有优势。

Dramatic increases in the knowledge of basic disease mechanisms from the laboratory are slow to find the bedside, clinic or general population. These delays are due,in part, to a lack of enough well-trained clinical researchers to translate scientific discoveries in human populations. Recognizing this deficit, the University of Minnesota and its Academic Health Center (AHC) developed a strategic plan in 2003 prioritizing clinical research (CR) at all University levels from undergraduates to the senior faculty. The proposed K12 program fits well into those plans and will enhance the substantial Minnesota CR investment. This K12 proposal embraces the spectrum of CR from observational epidemiology to clinical trials to outcomes research. Recognizing the multidisciplinary nature of CR, we include the Schools of Dentistry, Medicine, Nursing, Pharmacy and Public Health in CR scholar identification, training and development. These disciplines have a history of working together to provide leadership for CR. Beginning with clinical specialty fellows, postdoctoral students and junior faculty, we will select CR scholars to participate in current and new coursework from an ongoing K30 grant. Advised by three-person multidisciplinary mentor teams, including a biostatistician, the scholars will access substantial resources and infrastructure in the AHC including: 1) Skilled, experienced and enthusiastic senior mentors; 2) Biostatisticians with an international reputation for CR; 3) A General Clinical Research Center (GCRC) with a 25-year record of productivity; 4) A pharmaceutical center; 5) Veterans Administration and Hennepin County hospitals with diverse populations; 6) A minority recruitment program; 7) A substantial portfolio of federal and industry funded CR projects,and; 8) A proposed Shared Clinical Research Support Group. There is a history of collaboration among AHC schools in multidisciplinary CR using a team approach. This proposal expands on a successful CR enterprise in an institution with a ten-year strategic investment plan. The goal is to improve health and cure diseases through CR. This proposal merges many University of Minnesota strengths in a systematic, focused career development training program for NIH CR scholars.