Novel Nanofiber-reinforced All-ceramic Dental Materials

描述：新型连续、无纺布氧化纳米纤维将用于设计、生产和测试一种新型的全陶瓷材料，用于牙科修复应用。工作假设是，这些新的纳米纤维/玻璃系统将比该领域使用的最先进技术具有更高的机械质量。两位材料科学家(dr。Dzenis和Larsen（分别为联合项目负责人和项目负责人）将在第一阶段与内布拉斯加大学医学中心医学院的一名教员（外部顾问Thomas Salinas博士）合作。目前全陶瓷修复研究的重点之一是开发可靠的大跨后牙固定局部义齿（fpd）。这将是中心产品开发领域之一，提议的技术将朝着商业化阶段发展。拟议的研发工作符合国家牙科和颅面研究所（NIDCR）的使命和当前的战略研究领域。基于氧化铝、尖晶石、氧化锆、莫来石或其组合的密集连续纤维增强支架，预计新型玻璃渗透材料将具有优异的抗裂纹扩展性能，从而生产出具有优异美学和机械品质的牙科陶瓷。在第一阶段，重点将放在第一批选定的纳米玻璃纤维材料的生产上，它们的机械测试（例如，弯曲强度和断裂韧性），以及它们的微观结构表征（例如，孔隙率和缺陷数量）。

DESCRIPTION: Novel continuous, non-woven oxide nanofibers will be used to design, produce and test a new class of allceramic materials for restorative Dental applications. The working hypothesis is that these new nanofiber/glass systems will be of significantly higher mechanical quality than state-of-the-art technologies used in the field. Two materials scientists (Drs. Dzenis and Larsen, co-PI and PI, respectively) will collaborate with a faculty member from the College of Medicine, University of Nebraska Medical Center (external consultant, Dr. Thomas Salinas) during Phase I. One of the current topics of emphasis in allceramic restorations research is on developing reliable large-span posterior fixed partial dentures (FPDs). This will be one of the central product development areas that the proposed technology will target toward the commercialization phase. The proposed R and D effort is in line with the mission and current strategic research areas of the National Institute of Dental and Craniofacial Research (NIDCR). It is anticipated that the novel glass-infiltrated materials will have excellent crack propagation resistance thanks to dense and continuous fibrous reinforcing scaffolds based on alumina, spinel, zirconia, mullite, or a combination of them to produce Dental ceramics with superior esthetic and mechanical qualities. During Phase I, emphasis will be on production of the first few, selected nanofiber-glass materials of this class, their mechanical testing (e.g., flexural strength and fracture toughness), and their microstructure characterization (e.g., porosity and defect population).