Yale/NCI Cooperative Training Program in Cancer Epidemiology

描述（由申请人提供）：这是一个新颖的合作培训项目，其总体目标是培养生活方式和人类癌症风险环境决定因素领域最优秀、最聪明的学生。该提案包括院士和NIH内部科学家之间的合作，该安排的主要合作伙伴是耶鲁大学流行病学和公共卫生系（EPH）和国家癌症研究所癌症流行病学和遗传学部（DCEG）。这种独特的合作关系利用了耶鲁大学的学术优势，NCI的研究资源，以及这两个机构的研究优势，这两个机构都以其在癌症流行病学和遗传学方面的研究而闻名于世。此外，这两个合作伙伴在先前的研究和培训合作方面有着悠久的历史，其中许多涉及博士生。拟议的培训计划将培训学生评估人类癌症风险的生活方式决定因素的现代方法，重点是人类癌症风险的营养，环境和职业决定因素，包括它们与遗传因素的相互作用。入选这一独特培训项目的4名博士预科候选人将由耶鲁大学研究人员和NCI研究人员共同指导。该培训计划的实质是，在入学后，博士预科学生将在公共卫生学院接受2年的教学指导，这是一所经过认证的公共卫生学院。课程将强调流行病学和生物统计学的方法培训，内容培训包括癌症流行病学、营养流行病学、环境/职业流行病学、分子和遗传流行病学以及癌症生物学等多个领域。在两年的课堂学习结束后，学生们将在耶鲁参加资格考试，然后完成论文简介。作为论文大纲流程的一部分，学生必须确定一个论文咨询委员会，该委员会由两名来自耶鲁大学的教员（其中至少一名是高级导师）和两名来自NCI的教员组成。然后学生转到NCI进行论文研究。学生将满足耶鲁大学博士学位的所有要求，其中包括一年的助教（TA）经验要求，通常在第二年完成。博士前培训计划将由EPH和DCEG的代表组成的指导委员会管理。我们期望这个项目的毕业生将成为未来癌症流行病学和遗传学领域的领导者。

DESCRIPTION (provided by applicant): This proposal is for a novel cooperative training program whose overall goal is to train the best and brightest students in the area of lifestyle and environmental determinants of human cancer risk. The proposal consists of a partnering between academicians and NIH intramural scientists, with the primary partners in this arrangement being Yale University's Department of Epidemiology and Public Health (EPH), and the National Cancer Institute's Division of Cancer Epidemiology and Genetics (DCEG). This unique partnership draws upon the academic strengths of Yale University, the research resources at NCI, and the research strengths of these two institutions, both of which are internationally known for their research in cancer epidemiology and genetics. In addition, these two partners have a strong history of prior research and training collaborations, many involving pre-doctoral students. The proposed training program will train students in modem methodologies for evaluating lifestyle determinants of human cancer risk, with an emphasis on nutritional, environmental, and occupational determinants of human cancer risk including their interactions with genetic factors. A total of 4 pre-doctoral candidates selected into this unique training program will be jointly mentored by Yale investigators and NCI investigators. The essence of this training program is that upon matriculation, pre-doctoral candidates will receive 2 years of didactic instruction at EPH, which is an accredited School of Public Health. Coursework will emphasize methods training in epidemiology and biostatistics, with content training in a variety of areas including cancer epidemiology, nutritional epidemiology, environmental / occupational epidemiology, molecular and genetic epidemiology, and cancer biology. At the end of the two-year classroom experience, students will take their qualifying exams at Yale, and then complete a thesis prospectus. As part of the thesis prospectus process, students must identify a Dissertation Advisory Committee, composed of two faculty members from Yale (at least one of whom is a senior mentor) and two from NCI. Students then move to the NCI for dissertation research. Students will meet all requirements for the Ph.D. at Yale, which includes a one-year teaching assistant (TA) experiential requirement, usually done during the second year. The pre-doctoral training program will be administered by a Steering Committee with representation from both EPH and DCEG. We anticipate that graduates of this program will be uniquely qualified to be future leaders in the field of cancer epidemiology and genetics.