Yale/NCI Cooperative Training Program in Cancer Epidemiology

描述(由申请人提供)：这项建议是为了继续一个非常成功的研究生伙伴计划(GPP)，其总体目标是在生活方式和人类癌症风险的环境决定因素领域培养最优秀和最聪明的学生。该提案包括院士和NIH内部科学家之间的合作，这一安排的主要合作伙伴是耶鲁大学流行病学和公共卫生系(EPH)和国家癌症研究所的癌症流行病学和遗传学部门(DCEG)。这一独特的伙伴关系利用了耶鲁大学的学术优势、NCI的资源和专业知识以及这两个机构的研究优势，这两个机构都以癌症流行病学和遗传学的研究而闻名国际。合作培训计划培训学生使用现代方法评估人类癌症风险的生活方式决定因素，重点是营养、环境和职业决定因素，包括它们与遗传因素的相互作用。被选入这一独特培训计划的博士前候选人由耶鲁大学教职员工和NCI调查人员联合指导。入学后，博士前考生将在EPH接受长达2年的教学，EPH是一所经认可的公共卫生学院。课程强调流行病学和生物统计学的方法培训，内容包括癌症流行病学、营养流行病学、环境/职业流行病学、分子和遗传流行病学以及癌症生物学。在授课经历结束后，学生们参加耶鲁大学的资格考试，然后转到NCI。学生们确定论文主题，撰写论文说明书，并确定由耶鲁大学的两名教职员工(至少其中一人是资深导师)和NCI的两名教职员工组成的论文咨询委员会。学生符合耶鲁大学博士学位的所有要求，其中包括一年的助教(TA)经验要求。博士前培训计划由一个由EPH和DCEG代表组成的指导委员会管理。这个项目的毕业生是唯一有资格成为未来癌症流行病学和遗传学领域的领导者。

DESCRIPTION (provided by applicant): This proposal is to continue a highly successful graduate partnership program (GPP) whose overall goal is to train the best and brightest students in the area of lifestyle and environmental determinants of human cancer risk. The proposal consists of a partnering between academicians and NIH intramural scientists, with the primary partners in this arrangement being Yale University's Department of Epidemiology and Public Health (EPH), and the National Cancer Institute's Division of Cancer Epidemiology and Genetics (DCEG). This unique partnership draws upon the academic strengths of Yale University, the resources and expertise at NCI, and the research strengths of these two institutions, both of which are internationally known for their research in cancer epidemiology and genetics. The cooperative training program trains students in modern methodologies for evaluating lifestyle determinants of human cancer risk, with an emphasis on nutritional, environmental, and occupational determinants including their interactions with genetic factors. Pre-doctoral candidates selected into this unique training program are jointly mentored by Yale faculty and NCI investigators. Upon matriculation, pre-doctoral candidates receive up to 2 years of didactic instruction at EPH, which is an accredited School of Public Health. Coursework emphasizes methods training in epidemiology and biostatistics, with content training in a variety of areas including cancer epidemiology, nutritional epidemiology, environmental / occupational epidemiology, molecular and genetic epidemiology, and cancer biology. At the end of the didactic experience, students take their qualifying exams at Yale, and then subsequently relocate to the NCI. Students identify a thesis topic, write a thesis prospectus, and identify a Dissertation Advisory Committee comprised of two faculty members from Yale (at least one of whom is a senior mentor) and two from NCI. Students meet all requirements for the Ph.D. at Yale, which includes a one-year teaching assistant (TA) experiential requirement. The pre-doctoral training program is administered by a Steering Committee with representation from both EPH and DCEG. Graduates of this program are uniquely qualified to be future leaders in the field of cancer epidemiology and genetics.