Pediatric AIDS Clinical Trials Unit

儿科艾滋病临床试验单位

• 批准号: 6622147
• 负责人: COLEEN K. CUNNINGHAM
• 金额: $ 69万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-06-01 至 2007-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6622147
• 关键词: AIDS education /prevention; AIDS therapy; AIDS vaccines; HIV infections; antiAIDS agent; behavioral /social science research tag; children; cooperative study; human immunodeficiency virus 1; human pregnant subject; human subject; human therapy evaluation; immunotherapy; medically underserved population; pathologic process; patient oriented research; pediatric AIDS; rural area; vertical transmission

DESCRIPTION (provided by applicant): The Duke/North Carolina Children's AIDS Network {Duke/NC-CAN) Pediatric AIDS Clinical Trials Unit serves the tenth largest state in population by providing a statewide system of coordinated research efforts and care for HIV infected and exposed children. The hub for the program is at Duke University Medical Center, which has the largest single pediatric HIV clinic in North Carolina, and provides data entry, quality assurance, and grant-related financial management for the other centers in the network. There is a full subunit at the University of North Carolina, Chapel Hill, which provides care and has an emphasis on perinatal protocols. The PACTU also has a Duke-based Travel Team made up of a physician and nurse who travel to satellite clinics at the Carolinas Medical Center (Charlotte), Wake Forest University/Brenner Children's Hospital {Winston-Salem), and Carilion Medical Center for Children {Roanoke, VA). It is planned that another satellite clinic will be added at the East Carolina University Medical Center (Greenville, NC), although at present the Greenville clinic and one in Wilmington, NC, are used to screen patients for protocol eligibility. The Travel Team goes to the satellite clinics to see patients on PACTG protocols, carrying medications and case record forms with them. They return with completed case records and laboratory samples that will be processed at Duke or UNC. Physicians based at the satellite clinics provide the actual medical care and continuity. The UNC Retrovirology lab, supervised by Dr. Susan Fiscus, is one of the core PACTG retrovirology resource laboratories. Members of the PACTU participate in the Pediatric AIDS Clinical Trials Group at many levels: as protocol team members {including chairing or vice-chairing 11 protocols), members of administrative committees, and as a site accruing patients.

描述（由申请人提供）：杜克/北卡罗来纳州儿童艾滋病 网络{杜克/NC-CAN）儿科艾滋病临床试验单位提供第十次 人口最多的州，提供全州范围的协调系统， 研究工作和照顾受艾滋病毒感染和暴露的儿童。的枢纽 该项目是在杜克大学医学中心，其中有最大的单一 北卡罗来纳州的儿科艾滋病诊所，并提供数据输入，质量 保证和赠款有关的财务管理，为其他中心在 网络在北卡罗来纳州查珀尔大学有一个完整的子单位 希尔，提供护理，并强调围产期协议。的 PACTU还拥有一个由医生和护士组成的杜克旅行团队， 前往威克市的科琳娜斯医疗中心（夏洛特）的卫星诊所 森林大学/布伦纳儿童医院（温斯顿-塞勒姆），以及卡尔加里 儿童医疗中心（罗阿诺克，弗吉尼亚州）。计划另一个 东卡罗莱纳大学医学中心将增加一个卫星诊所 （格林维尔，NC），虽然目前格林维尔诊所和一个在 威尔明顿，NC用于筛选患者的方案合格性。的 旅行队前往卫星诊所，查看PACTG协议的患者， 携带药物和病例记录表。他们回来的时候 将在杜克处理的完整病例记录和实验室样本 或者说，卫星诊所的医生提供实际的医疗服务， 照顾和连续性。由苏珊博士监督的逆转录病毒实验室 Fiscus是PACTG逆转录病毒学的核心实验室之一。 PACTU成员参加儿科艾滋病临床试验小组 在许多级别：作为礼宾团队成员（包括主席或副主席） 11协议），行政委员会成员，并作为一个网站积累 患者