Pediatric AIDS Clinical Trials Unit

描述(申请人提供)：杜克/北卡罗来纳州儿童艾滋病 网络[Duke/NC-CAN]儿科艾滋病临床试验单位服务于第十个 人口最多的州通过提供全州范围的协调系统 研究工作和对感染艾滋病毒和接触艾滋病毒的儿童的关怀。的枢纽 该项目在杜克大学医学中心进行，该中心拥有最大的单项 北卡罗来纳州的儿童艾滋病毒诊所，并提供数据输入、质量 为其他中心提供担保和赠款相关的财务管理 网络。北卡罗来纳大学教堂分校有一个完整的子单元 Hill，它提供护理，并强调围产期协议。这个 PACTU还有一个以杜克为基地的旅行团队，由一名医生和护士组成，他们 前往维克卡罗莱纳医疗中心(夏洛特)的卫星诊所 森林大学/布伦纳儿童医院(温斯顿-塞勒姆)和Carilion 儿童医疗中心(弗吉尼亚州罗阿诺克)。计划再来一次 东卡罗来纳大学医疗中心将增设卫星诊所 (北卡罗来纳州格林维尔)，尽管目前格林维尔诊所和一家 北卡罗来纳州威尔明顿用于筛查患者的方案资格。这个 旅行队根据PACTG协议前往卫星诊所看望患者， 随身携带药物和病历表格。他们带着 完成的病例记录和实验室样本将在杜克大学处理 或者北卡罗来纳大学。驻扎在卫星诊所的医生提供实际的医疗 关爱和延续性。北卡罗来纳大学反病毒实验室，由苏珊博士监督 Fiscus，是PACTG的核心逆转录病毒资源实验室之一。 PACTU成员参加儿童艾滋病临床试验小组 在许多级别：作为礼宾小组成员{包括主持或副主持 11个协议)，管理委员会成员，并作为一个网站积累 病人。

DESCRIPTION (provided by applicant): The Duke/North Carolina Children's AIDS Network {Duke/NC-CAN) Pediatric AIDS Clinical Trials Unit serves the tenth largest state in population by providing a statewide system of coordinated research efforts and care for HIV infected and exposed children. The hub for the program is at Duke University Medical Center, which has the largest single pediatric HIV clinic in North Carolina, and provides data entry, quality assurance, and grant-related financial management for the other centers in the network. There is a full subunit at the University of North Carolina, Chapel Hill, which provides care and has an emphasis on perinatal protocols. The PACTU also has a Duke-based Travel Team made up of a physician and nurse who travel to satellite clinics at the Carolinas Medical Center (Charlotte), Wake Forest University/Brenner Children's Hospital {Winston-Salem), and Carilion Medical Center for Children {Roanoke, VA). It is planned that another satellite clinic will be added at the East Carolina University Medical Center (Greenville, NC), although at present the Greenville clinic and one in Wilmington, NC, are used to screen patients for protocol eligibility. The Travel Team goes to the satellite clinics to see patients on PACTG protocols, carrying medications and case record forms with them. They return with completed case records and laboratory samples that will be processed at Duke or UNC. Physicians based at the satellite clinics provide the actual medical care and continuity. The UNC Retrovirology lab, supervised by Dr. Susan Fiscus, is one of the core PACTG retrovirology resource laboratories. Members of the PACTU participate in the Pediatric AIDS Clinical Trials Group at many levels: as protocol team members {including chairing or vice-chairing 11 protocols), members of administrative committees, and as a site accruing patients.