Institutional Training Grant in Pediatric Infectious Disease

儿科传染病机构培训补助金

• 批准号: 8265228
• 负责人: COLEEN K. CUNNINGHAM
• 金额: $ 20.58万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-21 至 2016-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8265228
• 关键词: Childhood; Communicable Diseases; Grant; Training

DESCRIPTION (provided by applicant): The need for training pediatric infectious disease physician scientists has never been greater. Despite advances in vaccines and antimicrobials, new infectious diseases frequently emerge, re-emerge, or develop resistance to available therapies. These new infectious challenges require intense and diverse training such as that provided at Duke University Medical Center. The optimal training milieu requires astute clinicians knowledgeable in pediatric infectious diseases and skilled in modern scientific methods who can develop novel approaches to the understanding and treatment of childhood infections. The Duke University Pediatric Infectious Diseases training program has the environment and resources to provide exceptional training in clinical medicine and state of the art research training in basic science, clinical, health services, or global health investigation. The participating faculty is divided into four areas of research emphasis, areas selected to provide trainees with maximal opportunity to develop skills essential for addressing the major issues in childhood infectious diseases. The four areas include: 1) Bacterial Pathogenesis and Infection; 2) Fungal Pathogenesis and Infection; 3) Global Health and HIV/AIDS; and 4) Quantitative Sciences and Clinical Outcomes. A purposeful mixture of faculty from other clinical and basic science departments serves to foster collaborative interactions and to provide trainees with the opportunity to work closely with leaders in each field. A deliberate process for mentor selection is coordinated to ensure strong and consistent mentoring, and all program faculty mentors are established investigators with proven success in research and training. Training includes weekly mandatory seminars in a structured Core Curriculum, a 12-hour scientific writing course, mandatory graduate coursework, and regular oral presentations to laboratory and research groups. A Scientific Oversight Committee provides a written report to the Internal Advisory Committee semi-annually, followed by an annual review by the External Advisory Committee. Trainees are required to write at least two grant applications, present an abstract at a national or international meeting, and be a primary author on at least three peer-reviewed publications. Trainees also benefit from an extended formal mentorship program that will continue for three years after completing the training program, designed to facilitate transition into a successful academic career. This application requests support for one PGY5 trainee and two PGY6 trainees. This training program, linked with a detailed and robust mentoring and evaluation program, will allow trainees to develop the knowledge and understanding necessary to pursue independent research careers in academic pediatric infectious disease. This training grant will allow us to develop innovative pediatric physician-scientists fully prepared to pursue independent academic careers investigating critical issues in pediatric infectious diseases. The trainees will become the leaders in the field of infectious diseases and become key mentors to future pediatric physician-scientists. PUBLIC HEALTH RELEVANCE: Infectious diseases are among the leading causes of death in children worldwide and infectious disease mortality is increasing in the United States. Unfortunately, there is a paucity of physician scientists entering the field of pediatric infectious diseases with rigorous scientific training to pursue research toward combating this growing problem. The proposed training program will address this gap by developing outstanding pediatric infectious diseases physician scientists.

描述（由申请人提供）：培训儿科传染病医生科学家的需求从未如此之大。尽管疫苗和抗菌药物取得了进展，但新的传染病经常出现、重新出现或对现有疗法产生耐药性。这些新的传染性挑战需要密集和多样化的培训，如杜克大学医学中心提供的培训。最佳的培训环境需要精明的临床医生在儿科传染病知识和熟练的现代科学方法谁可以开发新的方法来理解和治疗儿童感染。杜克大学儿科传染病培训计划拥有环境和资源，可提供临床医学方面的特殊培训，以及基础科学、临床、卫生服务或全球卫生调查方面的最先进研究培训。参与的教师分为四个研究重点领域，选择这些领域是为了为学员提供最大的机会，培养解决儿童传染病主要问题所必需的技能。这四个领域包括：1）细菌发病机制和感染; 2）真菌发病机制和感染; 3）全球健康和艾滋病毒/艾滋病;和4）定量科学和临床结果。来自其他临床和基础科学部门的教师有目的的混合物有助于促进协作互动，并为学员提供与每个领域的领导者密切合作的机会。一个深思熟虑的导师选择过程是协调，以确保强大和一致的指导，所有程序教师导师建立调查与研究和培训证明成功。培训包括每周一次的结构化核心课程强制性研讨会，12小时的科学写作课程，强制性研究生课程，以及定期向实验室和研究小组进行口头报告。科学监督委员会每半年向内部咨询委员会提交一份书面报告，然后由外部咨询委员会进行年度审查。要求学员至少写两份资助申请，在国家或国际会议上提交摘要，并在至少三份同行评审的出版物上担任主要作者。学员还受益于一个扩展的正式导师计划，该计划将在完成培训计划后持续三年，旨在促进过渡到一个成功的学术生涯。此应用程序要求支持一名PGY 5受训人员和两名PGY 6受训人员。该培训计划与详细而强大的指导和评估计划相联系，将使学员能够发展必要的知识和理解，以追求学术儿科传染病的独立研究事业。这项培训补助金将使我们能够培养创新的儿科医生科学家，他们完全准备好从事独立的学术事业，调查儿科传染病的关键问题。学员将成为传染病领域的领导者，并成为未来儿科医生科学家的关键导师。 公共卫生相关性：传染病是全世界儿童死亡的主要原因之一，在美国，传染病死亡率正在上升。不幸的是，很少有医生科学家进入儿科感染性疾病领域，接受严格的科学培训，从事研究，以应对这一日益严重的问题。拟议的培训计划将通过培养杰出的儿科传染病医生科学家来解决这一差距。