CORE--BIOCHEMISTRY CORE

生物化学核心正在建立，以满足 蛋白质分离和结构表征的个别项目。 这个核心已经从先前项目2的一部分演变而来， 黑色素瘤相关抗原的生物化学和差异表达。 因为我们分析少量蛋白质的方法是 黑色素瘤和黑素细胞系的可获得性有所改善，他们 发展到现在大多数所需的程序都相对 例行公事，尽管它们仍然高度复杂和技术上 要求很高。这些资源已经进化到了更多的程度 适当地放在核心中，而不是基础研究项目。在……里面 此外，多个项目对这些生化分析的需求是 稳步扩张。

The Biochemistry Core is being established to address a growing need by the individual projects for protein isolation and structural characterization. This core has evolved out of a portion of the previous Project 2, "Biochemistry and Differential Expression of Melanoma-associated Antigens". As our methods for analysis of the small amounts of proteins that are available from melanoma and melanocyte cell lines have improved, they have developed to the point where most required procedures are now relatively routine, although they remain highly sophisticated and technically demanding. These resources have evolved to the point where they are more appropriately placed in a Core as opposed to a basic research project. In addition, the need for these biochemical analyses by multiple projects is steadily expanding.