PATIENT ORIENTED RESEARCH IN AGING

本申请提出了Albert L.萧博士，M.S.P. H对于职业生涯中期 NIA的以患者为导向的研究者奖。 萧医生 1985年完成训练。 他职业生涯的前半部分 作为加州大学洛杉矶分校的教员和部门主管。 他一直在山上 西奈自1995年以来，他一直在3个部门内工作， 一个老龄化临床研究项目 在过去的十年里，他 是7名医生的主要导师， 新增7名医生。 他目前是3名学生的主要导师。 教师和2名研究员在老龄化。 候选人提议建造 一个以病人为导向的研究计划，重点是损伤， 导致功能状态差和残疾的疾病， 衰老 这项工作将集中在髋部骨折的研究，但将包括 以及其他与衰老有关的损伤和疾病。 的目标 该计划将建立一个老龄化临床研究计划， 吸引了来自各种临床研究人员的参与， 学科，以解决老年临床的多方面问题， 综合征 具体目标是：1）指导老年医学培训人员 医学和其他临床学科进行以病人为本 研究在老龄化; 2）使用候选人正在进行的研究， 髋部骨折治疗的医疗和康复方面作为一个平台 用于指导研究; 3）创建支持基础设施 以病人为本的老龄化研究;以及4）支持 以病人为中心的老龄化研究 建议的指导病人- 定向研究计划将为受指导的研究人员提供 一系列直接与患者互动的经验，包括1） 与患者互动以获得同意; 2）访谈和 检查受试者收集数据; 3）检查受试者和监测 他们对干预措施的反应;以及4）进行测试或程序 关于主题实践研究经验将得到补充， 1)课堂经验与受训者的需求相匹配，2）更少 以成人学习原则为基础的正式课程， 一系列可能被统称为“生存”的话题 衰老临床研究人员的技能。

This application proposes Albert L. Siu, M.D., M.S.P.H. for a Midcareer Investigator Award in Patient-oriented Research from the NIA. Dr. Siu completed his training in 1985. He spent the first part of his career as a faculty member and division chief at UCLA. He has been at Mount Sinai since 1995 where he has been working within 3 departments to build a clinical research program in aging. In the last ten years, he has been the primary mentor for 7 physicians and a supporting mentor to an additional 7 physicians. He is currently the primary mentor to 3 faculty members and 2 fellows in aging. The candidate proposes to build a program of patient-oriented research focused on the impairments and diseases that contribute to poor functional status and disability in aging. This work will focus on hip fracture research, but will include other aging-related impairments and diseases as well. The objective of the program will be to build a clinical research program in aging that engages the participation of researchers from a variety of clinical disciplines to address the multi-faceted aspects of geriatric clinical syndromes. The specific aims are 1) to mentor trainees in geriatric medicine and in other clinical disciplines to conduct patient-oriented research in aging; 2) to use the candidate's ongoing research on the medical and rehabilitative aspects of hip fracture care as one platform for mentored research; 3) to create an infrastructure to support patient-oriented research in aging; and 4) to support pilot studies in patient-oriented research in aging. The proposed mentored patient- oriented research program will provide the mentored investigators with a range of experiences in direct patient interaction including 1) interacting with patients to obtain consent; 2) interviewing and examining subjects to collect data; 3) examining subjects and monitoring their response to interventions; and 4) performing tests or procedures on subjects. The hands-on research experience will be complemented by 1) classroom experiences matched to the trainee's needs and 2) less formal sessions that are grounded in adult learning principles to cover a series of topics that collectively might be considered "survival" skills for clinical researchers in aging.