Patient-Oriented Research in Aging

描述(由申请人提供)：此申请支持将以患者为中心的研究的职业中期研究员奖从NIA续期到Albert L.Siu，M.D.，M.S.P.H.自1995年以来，Siu博士一直在西奈山工作，在那里他在3个部门(卫生政策，医学和老年病学)工作，建立了一个关于老龄的临床研究计划。2002年11月，他成为老年病学会的主席。在他目前获奖的过程中，他一直是11名初级调查员的主要或次要导师，这些人获得了10个职业发展奖。他目前是4名学员的主要研究导师和4名学员的次要研究导师。 指导者。萧如彬博士在衰老方面的临床研究侧重于功能状态，以及导致功能低下的既往损伤和疾病实体。他建议开展比他个人研究兴趣更广泛的指导活动，以认识到a)潜在被指导者的不同兴趣，b)功能损害和其他老年临床综合征研究之间的相当大的重叠，以及c)吸引其他临床学科的研究人员参与的重要性，这些研究专门研究导致功能损害和老年临床综合征的损害和疾病实体。这项申请的具体目的是：1)指导老年病学和其他临床学科的学员进行以患者为中心的老龄研究；2)以候选人及其学员正在进行的研究为平台，支持新的学员及其研究；3)加强基础设施，以支持以患者为中心的老龄研究；以及4)支持以患者为中心的老龄研究的试点研究。拟议的以患者为导向的指导研究计划将为指导调查人员提供涉及候选人和他的指导对象的项目的直接研究经验。与实践研究经验相辅相成的是：1)与学员的需求相匹配的课堂体验；2)每周一次的老龄临床研究实验室会议；以及3)基于成人学习原则的不那么正式的会议，涵盖一系列共同可能被视为临床研究人员在老龄化中的“生存”技能的主题。

DESCRIPTION (provided by applicant): This application supports a renewal of the Midcareer Investigator Award in Patient-Oriented Research from the NIA to Albert L. Siu, M.D., M.S.P.H. Dr. Siu has been at Mount Sinai since 1995 where he has worked within 3 departments (Health Policy, Medicine, and Geriatrics) to build a clinical research program in aging. In November 2002, he became the Chairman of Geriatrics. Over the course of his current award, he has been the primary or secondary mentor to 11 junior investigators who have received 10 career development awards. He is currently active as the primary research mentor to 4 mentees and as the secondary research mentor to 4 mentees. Dr. Siu's clinical research in aging focuses on functional status and on the antecedent impairments and disease entities that contribute to poor function. He is proposing mentoring activities that have a focus broader than his personal research interests in recognition of a) the varied interests of potential mentees, b) the considerable overlap between research in functional impairment and in other geriatric clinical syndromes, and c) the importance of engaging the participation of researchers from other clinical disciplines specializing in the impairments and disease entities that contribute to functional impairment and geriatric clinical syndromes. The specific aims of this application are to: 1) to mentor trainees in geriatrics and other clinical disciplines to conduct patient-oriented research in aging; 2) to use the candidate's and his mentees' ongoing research as a platform to support new mentees and their research; 3) to enhance the infrastructure to support patient-oriented research in aging; and 4) to support pilot studies in patient-oriented research in aging. The proposed mentored patient-oriented research program will provide the mentored investigators with direct research experiences in projects involving the candidate and his mentees. The hands-on research experience will be complemented by 1) classroom experiences matched to the trainee's needs, 2) a weekly lab meeting for clinical research in aging; and 3) less formal sessions that are grounded in adult learning principles to cover a series of topics that collectively might be considered "survival" skills for clinical researchers in aging.