DIFFRACTION OF GDP DISSOCIATION INHIBITOR (GDI) FROM DROSOPHILA MELANOGSTER

果蝇 GDP 解离抑制剂 (GDI) 的衍射

• 批准号: 6658466
• 负责人: GABRIEL WAKSMAN
• 金额: $ 14.32万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-03-01 至 2003-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6658466
• 关键词: bioimaging /biomedical imaging; biomedical resource; human tissue; radiography; structural biology

GDP dissociation inhibitor (GDI) is a regulator of small ras-like GTPases of the rab subfamily. The rab GTPases control steps in vesicular transport, involving both secretion and endocytosis. Moreover, in the cell-division mutant of Drosophila, quartet, rab GDI is shifted in isoelectric point, suggesting that GDI may play a role in governing the onset and progression of cell division.

GDP 解离抑制剂 (GDI) 是小 ras 样蛋白的调节剂 rab 亚科的 GTPases。 rab GTPases 控制步骤 囊泡运输，涉及分泌和内吞作用。 此外，在果蝇细胞分裂突变体中，四联体，rab GDI 等电点发生变化，表明 GDI 可能发挥了作用 控制细胞分裂的开始和进展。