CRYOPRESERVED CRYSTALS OF HEMOLIN, FASCICLIN III & HIGH PH NEONATAL FC RECEPTOR
CRYOPRESERVED CRYSTALS OF HEMOLIN, FASCICLIN III & HIGH PH NEONATAL FC RECEPTOR
批准号:
6658702
负责人:
Pamela J Bjorkman
金额:
$14.32万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2002
资助国家:
美国
项目状态:
已结题
起止时间:
2002-03-01 至 2003-02-28
中文摘要
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英文摘要
Proper function of a-lytic protease requires the presence of its
N-terminal pro region, which catalyzes an as yet unidentified step in
the folding of this enzyme. In order to better understand the folding
mechanism, we are using x-ray crystallography to determine the
structure of the pro region, both by itself and in a complex with
folded protease. We have engineered several mutants containing
cysteines to facilitate the preparation of heavy atom derivatives for
multiple isomorphous replacement.
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Structural Characterization of Coronavirus Antibodies Raised by Infection and Vaccination
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批准号:10327994
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项目类别:
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资助金额:$150.76万
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财政年份:2022
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负责人:Pamela J Bjorkman
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依托单位:
CHEETAH Center for the Structural Biology of HIV Infection, Restriction, and Viral Dynamics
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批准号:10508317
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项目类别:
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资助金额:$116.03万
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财政年份:2022
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负责人:Pamela J Bjorkman
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依托单位:
Structural Characterization of Coronavirus Antibodies Raised by Infection and Vaccination
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批准号:10841242
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项目类别:
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资助金额:$97.15万
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财政年份:2022
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负责人:Pamela J Bjorkman
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依托单位:
CHEETAH Center for the Structural Biology of HIV Infection, Restriction, and Viral Dynamics
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批准号:10663363
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项目类别:
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资助金额:$170.74万
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财政年份:2022
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负责人:Pamela J Bjorkman
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依托单位:
Characterization of HCV vaccine induced-neutralizing antibody response in non-human primates
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批准号:10398152
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项目类别:
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资助金额:$36.86万
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财政年份:2021
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负责人:Pamela J Bjorkman
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依托单位:
Characterization of HCV vaccine induced-neutralizing antibody response in non-human primates
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批准号:10614987
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项目类别:
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资助金额:$37.14万
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财政年份:2021
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负责人:Pamela J Bjorkman
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依托单位:
Characterization of HCV vaccine induced-neutralizing antibody response in non-human primates
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批准号:10205734
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项目类别:
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资助金额:$39.23万
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财政年份:2021
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负责人:Pamela J Bjorkman
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依托单位:
Project 1: Immunization strategies to elicit broadly neutralizing antibodies against HIV-1
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批准号:10458249
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项目类别:
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资助金额:$14.0万
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财政年份:2021
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负责人:Pamela J Bjorkman
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依托单位:
Enhancement of the HIV Antibody Database tool for Open Science
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批准号:10406832
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项目类别:
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资助金额:$14.0万
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财政年份:2021
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负责人:Pamela J Bjorkman
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依托单位:
Project 2
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批准号:9982207
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项目类别:
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资助金额:$58.5万
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财政年份:2018
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负责人:Pamela J Bjorkman
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依托单位:
Project 2
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批准号:10454950
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项目类别:
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资助金额:$50.97万
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财政年份:2018
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负责人:Pamela J Bjorkman
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依托单位:
Project 2
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批准号:10216968
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项目类别:
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资助金额:$58.5万
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财政年份:2018
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负责人:Pamela J Bjorkman
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依托单位:
Targeting the HIV reservoir using optimized anti-HIV antibodies
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批准号:9273865
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项目类别:
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资助金额:$41.08万
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财政年份:2017
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负责人:Pamela J Bjorkman
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依托单位:
Targeting the HIV reservoir using optimized anti-HIV antibodies
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批准号:10179304
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项目类别:
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资助金额:$41.08万
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财政年份:2017
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负责人:Pamela J Bjorkman
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依托单位:
Core A: Automated Cell/Biochemical Assays Core
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批准号:10307760
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项目类别:
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资助金额:$41.84万
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财政年份:2013
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负责人:Pamela J Bjorkman
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依托单位:
Development Structure and Function of Broadly Neutralizing anti-HIV Antibodies
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批准号:8617121
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项目类别:
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资助金额:$263.67万
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财政年份:2013
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负责人:Pamela J Bjorkman
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依托单位:
Development Structure and Function of Broadly Neutralizing anti-HIV Antibodies
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批准号:8786046
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项目类别:
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资助金额:$210.03万
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财政年份:2013
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负责人:Pamela J Bjorkman
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依托单位:
Core A: Automated Cell/Biochemical Assays Core
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批准号:10710276
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项目类别:
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资助金额:$41.48万
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财政年份:2013
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负责人:Pamela J Bjorkman
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依托单位:
Core C: Administrative Core
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批准号:10710275
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项目类别:
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资助金额:$13.84万
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财政年份:2013
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负责人:Pamela J Bjorkman
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依托单位:
Project 2: Design and screening for immunogens to efficiently elicit anti-HIV-1 bNAbs
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批准号:10307762
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项目类别:
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资助金额:$63.6万
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财政年份:2013
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负责人:Pamela J Bjorkman
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依托单位:
海外基金